| Nomenclature |
|---|
| HGNC (Hugo) | KAT7 17016 |
| Cards |
|---|
| Entrez_Gene (NCBI) | KAT7 11143 lysine acetyltransferase 7 |
| Aliases | HBO1; HBOA; MYST2; ZC2HC7 |
| GeneCards (Weizmann) | KAT7 |
| Ensembl hg19 (Hinxton) | ENSG00000136504 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000136504 [Gene_View] ENSG00000136504 [Sequence] chr17:49788619-49829096 [Contig_View] KAT7 [Vega] |
| ICGC DataPortal | ENSG00000136504 |
| TCGA cBioPortal | KAT7 |
| AceView (NCBI) | KAT7 |
| Genatlas (Paris) | KAT7 |
| WikiGenes | 11143 |
| SOURCE (Princeton) | KAT7 |
| Genetics Home Reference (NIH) | KAT7 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | KAT7 - chr17:49788619-49829096 + 17q21.33 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | KAT7 - 17q21.33 [Description] (hg19-Feb_2009) |
| GoldenPath | KAT7 - 17q21.33 [CytoView hg19] KAT7 - 17q21.33 [CytoView hg38] |
| ImmunoBase | ENSG00000136504 |
| Mapping of homologs : NCBI | KAT7 [Mapview hg19] KAT7 [Mapview hg38] |
| OMIM | 609880 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AF074606 AF140360 AF217502 AK023890 AK122932 |
| RefSeq transcript (Entrez) | NM_001199155 NM_001199156 NM_001199157 NM_001199158 NM_001346706 NM_007067 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | KAT7 |
| Cluster EST : Unigene | Hs.21907 [ NCBI ] |
| CGAP (NCI) | Hs.21907 |
| Alternative Splicing Gallery | ENSG00000136504 |
| Gene Expression | KAT7 [ NCBI-GEO ] KAT7 [ EBI - ARRAY_EXPRESS ]
KAT7 [ SEEK ] KAT7 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | KAT7 [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 11143 |
| GTEX Portal (Tissue expression) | KAT7 |
| Human Protein Atlas | ENSG00000136504-KAT7 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | O95251 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | O95251 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | O95251 |
| Splice isoforms : SwissVar | O95251 |
| Catalytic activity : Enzyme | 2.3.1.48 [ Enzyme-Expasy ] 2.3.1.482.3.1.48 [ IntEnz-EBI ] 2.3.1.48 [ BRENDA ] 2.3.1.48 [ KEGG ] |
| PhosPhoSitePlus | O95251 |
| Domaine pattern : Prosite (Expaxy) | MYST_HAT (PS51726) ZF_CCHHC (PS51802) |
| Domains : Interpro (EBI) | Acyl_CoA_acyltransferase HAT_MYST-type WH-like_DNA-bd_sf Znf_C2HC Znf_C2HC_sf |
| Domain families : Pfam (Sanger) | MOZ_SAS (PF01853) zf-C2HC (PF01530) |
| Domain families : Pfam (NCBI) | pfam01853 pfam01530 |
| Conserved Domain (NCBI) | KAT7 |
| DMDM Disease mutations | 11143 |
| Blocks (Seattle) | KAT7 |
| PDB (RSDB) | 5GK9 |
| PDB Europe | 5GK9 |
| PDB (PDBSum) | 5GK9 |
| PDB (IMB) | 5GK9 |
| Structural Biology KnowledgeBase | 5GK9 |
| SCOP (Structural Classification of Proteins) | 5GK9 |
| CATH (Classification of proteins structures) | 5GK9 |
| Superfamily | O95251 |
| Human Protein Atlas [tissue] | ENSG00000136504-KAT7 [tissue] |
| Peptide Atlas | O95251 |
| HPRD | 07135 |
| IPI | IPI00180764 IPI00909215 IPI00909397 IPI00953599 IPI00792061 IPI00964824 IPI00966972 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | O95251 |
| IntAct (EBI) | O95251 |
| FunCoup | ENSG00000136504 |
| BioGRID | KAT7 |
| STRING (EMBL) | KAT7 |
| ZODIAC | KAT7 |
| Ontologies - Pathways |
|---|
| QuickGO | O95251 |
| Ontology : AmiGO | histone acetyltransferase complex histone acetyltransferase complex nuclear chromatin DNA-binding transcription factor activity, RNA polymerase II-specific DNA replication origin binding histone acetyltransferase activity protein binding nucleus nucleus nucleoplasm nucleoplasm nucleolus cytosol DNA replication regulation of transcription, DNA-templated zinc ion binding H4 histone acetyltransferase activity internal peptidyl-lysine acetylation stress-activated protein kinase signaling cascade histone binding histone H3 acetylation histone H3 acetylation histone H4-K5 acetylation histone H4-K8 acetylation histone H4-K12 acetylation histone H4-K16 acetylation transcription regulatory region DNA binding negative regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II response to sorbitol response to hydroxyurea response to actinomycin D response to dithiothreitol response to anisomycin positive regulation of histone H4 acetylation positive regulation of protein localization to nucleus |
| Ontology : EGO-EBI | histone acetyltransferase complex histone acetyltransferase complex nuclear chromatin DNA-binding transcription factor activity, RNA polymerase II-specific DNA replication origin binding histone acetyltransferase activity protein binding nucleus nucleus nucleoplasm nucleoplasm nucleolus cytosol DNA replication regulation of transcription, DNA-templated zinc ion binding H4 histone acetyltransferase activity internal peptidyl-lysine acetylation stress-activated protein kinase signaling cascade histone binding histone H3 acetylation histone H3 acetylation histone H4-K5 acetylation histone H4-K8 acetylation histone H4-K12 acetylation histone H4-K16 acetylation transcription regulatory region DNA binding negative regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II response to sorbitol response to hydroxyurea response to actinomycin D response to dithiothreitol response to anisomycin positive regulation of histone H4 acetylation positive regulation of protein localization to nucleus |
| NDEx Network | KAT7 |
| Atlas of Cancer Signalling Network | KAT7 |
| Wikipedia pathways | KAT7 |
| Orthology - Evolution |
|---|
| OrthoDB | 11143 |
| GeneTree (enSembl) | ENSG00000136504 |
| Phylogenetic Trees/Animal Genes : TreeFam | KAT7 |
| HOGENOM | O95251 |
| Homologs : HomoloGene | KAT7 |
| Homology/Alignments : Family Browser (UCSC) | KAT7 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Mitelman | BCAS3/KAT7 [17q23.2/17q21.33] [t(17;17)(q21;q23)] |
| Fusion : Mitelman | KAT7/AXIN2 [17q21.33/17q24.1] [t(17;17)(q21;q24)] |
| Fusion : Mitelman | KAT7/IGF2BP1 [17q21.33/17q21.32] [t(17;17)(q21;q21)] |
| Fusion Portal | BCAS3 17q23.2 KAT7 17q21.33 BRCA |
| Fusion Portal | KAT7 17q21.33 AXIN2 17q24.1 BRCA |
| Fusion Portal | KAT7 17q21.33 IGF2BP1 17q21.32 THCA |
| Fusion : Quiver | KAT7 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | KAT7 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | KAT7 |
| dbVar | KAT7 |
| ClinVar | KAT7 |
| 1000_Genomes | KAT7 |
| Exome Variant Server | KAT7 |
| ExAC (Exome Aggregation Consortium) | ENSG00000136504 |
| GNOMAD Browser | ENSG00000136504 |
| Varsome Browser | KAT7 |
| Genetic variants : HAPMAP | 11143 |
| Genomic Variants (DGV) | KAT7 [DGVbeta] |
| DECIPHER | KAT7 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | KAT7 |
| Mutations |
|---|
| ICGC Data Portal | KAT7 |
| TCGA Data Portal | KAT7 |
| Broad Tumor Portal | KAT7 |
| OASIS Portal | KAT7 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | KAT7 [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | KAT7 |
| Mutations and Diseases : HGMD | KAT7 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search KAT7 |
| DgiDB (Drug Gene Interaction Database) | KAT7 |
| DoCM (Curated mutations) | KAT7 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | KAT7 (select a term) |
| intoGen | KAT7 |
| Cancer3D | KAT7(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 609880 |
| Orphanet | |
| DisGeNET | KAT7 |
| Medgen | KAT7 |
| Genetic Testing Registry | KAT7
|
| NextProt | O95251 [Medical] |
| TSGene | 11143 |
| GENETests | KAT7 |
| Target Validation | KAT7 |
| Huge Navigator |
KAT7 [HugePedia] |
| snp3D : Map Gene to Disease | 11143 |
| BioCentury BCIQ | KAT7 |
| ClinGen | KAT7 |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 11143 |
| Chemical/Pharm GKB Gene | PA134886407 |
| Clinical trial | KAT7 |
| Miscellaneous |
|---|
| canSAR (ICR) | KAT7 (select the gene name) |
| DataMed Index | KAT7 |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 79 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | KAT7 |
| EVEX | KAT7 |
| GoPubMed | KAT7 |
| iHOP | KAT7 |
