| Nomenclature |
|---|
| HGNC (Hugo) | KAT7 17016 |
| Cards |
|---|
| Entrez_Gene (NCBI) | KAT7 lysine acetyltransferase 7 |
| Aliases | HBO1; HBOA; MYST2; ZC2HC7 |
| GeneCards (Weizmann) | KAT7 |
| Ensembl hg19 (Hinxton) | ENSG00000136504 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000136504 [Gene_View] ENSG00000136504 [Sequence] chr17:49788681-49835026 [Contig_View] KAT7 [Vega] |
| ICGC DataPortal | ENSG00000136504 |
| TCGA cBioPortal | KAT7 |
| AceView (NCBI) | KAT7 |
| Genatlas (Paris) | KAT7 |
| SOURCE (Princeton) | KAT7 |
| Genetics Home Reference (NIH) | KAT7 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | KAT7 - chr17:49788681-49835026 + 17q21.33 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | KAT7 - 17q21.33 [Description] (hg19-Feb_2009) |
| GoldenPath | KAT7 - 17q21.33 [CytoView hg19] KAT7 - 17q21.33 [CytoView hg38] |
| ImmunoBase | ENSG00000136504 |
| genome Data Viewer NCBI | KAT7 [Mapview hg19] |
| OMIM | 609880 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AF074606 AF140360 AF217502 AK023890 AK122932 |
| RefSeq transcript (Entrez) | NM_001199155 NM_001199156 NM_001199157 NM_001199158 NM_001346706 NM_007067 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | KAT7 |
| Alternative Splicing Gallery | ENSG00000136504 |
| Gene Expression | KAT7 [ NCBI-GEO ] KAT7 [ EBI - ARRAY_EXPRESS ]
KAT7 [ SEEK ] KAT7 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | KAT7 [ Firebrowse - Broad ] |
| Genevisible | Expression of KAT7 in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 11143 |
| GTEX Portal (Tissue expression) | KAT7 |
| Human Protein Atlas | ENSG00000136504-KAT7 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | O95251 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | O95251 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | O95251 |
| Splice isoforms : SwissVar | O95251 |
| PhosPhoSitePlus | O95251 |
| Domaine pattern : Prosite (Expaxy) | MYST_HAT (PS51726) ZF_CCHHC (PS51802) |
| Domains : Interpro (EBI) | Acyl_CoA_acyltransferase HAT_MYST-type WH-like_DNA-bd_sf Zf-MYST Znf_C2H2C Znf_C2H2C_sf |
| Domain families : Pfam (Sanger) | MOZ_SAS (PF01853) zf-C2HC (PF01530) zf-MYST (PF17772) |
| Domain families : Pfam (NCBI) | pfam01853 pfam01530 pfam17772 |
| Conserved Domain (NCBI) | KAT7 |
| Blocks (Seattle) | KAT7 |
| PDB (RSDB) | 5GK9 6MAJ 6MAK |
| PDB Europe | 5GK9 6MAJ 6MAK |
| PDB (PDBSum) | 5GK9 6MAJ 6MAK |
| PDB (IMB) | 5GK9 6MAJ 6MAK |
| Structural Biology KnowledgeBase | 5GK9 6MAJ 6MAK |
| SCOP (Structural Classification of Proteins) | 5GK9 6MAJ 6MAK |
| CATH (Classification of proteins structures) | 5GK9 6MAJ 6MAK |
| Superfamily | O95251 |
| Human Protein Atlas [tissue] | ENSG00000136504-KAT7 [tissue] |
| Peptide Atlas | O95251 |
| HPRD | 07135 |
| IPI | IPI00180764 IPI00909215 IPI00909397 IPI00953599 IPI00792061 IPI00964824 IPI00966972 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | O95251 |
| IntAct (EBI) | O95251 |
| BioGRID | KAT7 |
| STRING (EMBL) | KAT7 |
| ZODIAC | KAT7 |
| Ontologies - Pathways |
|---|
| QuickGO | O95251 |
| Ontology : AmiGO | histone acetyltransferase complex histone acetyltransferase complex chromosome, centromeric region nuclear chromatin natural killer cell differentiation DNA replication origin binding histone acetyltransferase activity histone acetyltransferase activity protein binding nucleus nucleus nucleoplasm nucleoplasm chromosome nucleolus cytosol DNA replication DNA repair regulation of transcription, DNA-templated zinc ion binding H4 histone acetyltransferase activity internal peptidyl-lysine acetylation regulation of DNA-dependent DNA replication initiation stress-activated protein kinase signaling cascade Piccolo NuA4 histone acetyltransferase complex positive regulation of DNA-templated transcription, elongation histone H3-K14 acetyltransferase complex histone binding histone H3 acetylation histone H4 acetylation histone H4-K5 acetylation histone H4-K8 acetylation histone H4-K12 acetylation histone H4-K16 acetylation histone H3-K14 acetylation positive regulation of erythrocyte differentiation positive regulation of DNA replication negative regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II response to sorbitol response to hydroxyurea response to actinomycin D response to dithiothreitol response to anisomycin positive regulation of histone H4 acetylation site of DNA damage positive regulation of protein localization to nucleus positive regulation of hematopoietic stem cell proliferation regulation of nucleotide-excision repair |
| Ontology : EGO-EBI | histone acetyltransferase complex histone acetyltransferase complex chromosome, centromeric region nuclear chromatin natural killer cell differentiation DNA replication origin binding histone acetyltransferase activity histone acetyltransferase activity protein binding nucleus nucleus nucleoplasm nucleoplasm chromosome nucleolus cytosol DNA replication DNA repair regulation of transcription, DNA-templated zinc ion binding H4 histone acetyltransferase activity internal peptidyl-lysine acetylation regulation of DNA-dependent DNA replication initiation stress-activated protein kinase signaling cascade Piccolo NuA4 histone acetyltransferase complex positive regulation of DNA-templated transcription, elongation histone H3-K14 acetyltransferase complex histone binding histone H3 acetylation histone H4 acetylation histone H4-K5 acetylation histone H4-K8 acetylation histone H4-K12 acetylation histone H4-K16 acetylation histone H3-K14 acetylation positive regulation of erythrocyte differentiation positive regulation of DNA replication negative regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II response to sorbitol response to hydroxyurea response to actinomycin D response to dithiothreitol response to anisomycin positive regulation of histone H4 acetylation site of DNA damage positive regulation of protein localization to nucleus positive regulation of hematopoietic stem cell proliferation regulation of nucleotide-excision repair |
| NDEx Network | KAT7 |
| Atlas of Cancer Signalling Network | KAT7 |
| Wikipedia pathways | KAT7 |
| Orthology - Evolution |
|---|
| OrthoDB | 11143 |
| GeneTree (enSembl) | ENSG00000136504 |
| Phylogenetic Trees/Animal Genes : TreeFam | KAT7 |
| HOGENOM | O95251 |
| Homologs : HomoloGene | KAT7 |
| Homology/Alignments : Family Browser (UCSC) | KAT7 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Mitelman | BCAS3/KAT7 [17q23.2/17q21.33] |
| Fusion : Mitelman | KAT7/AXIN2 [17q21.33/17q24.1] |
| Fusion : Mitelman | KAT7/IGF2BP1 [17q21.33/17q21.32] |
| Fusion Portal | BCAS3 17q23.2 KAT7 17q21.33 BRCA |
| Fusion Portal | KAT7 17q21.33 AXIN2 17q24.1 BRCA |
| Fusion Portal | KAT7 17q21.33 IGF2BP1 17q21.32 THCA |
| Fusion : Quiver | KAT7 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | KAT7 [hg38] |
| dbVar | KAT7 |
| ClinVar | KAT7 |
| Monarch | KAT7 |
| 1000_Genomes | KAT7 |
| Exome Variant Server | KAT7 |
| GNOMAD Browser | ENSG00000136504 |
| Varsome Browser | KAT7 |
| Genomic Variants (DGV) | KAT7 [DGVbeta] |
| DECIPHER | KAT7 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | KAT7 |
| Mutations |
|---|
| ICGC Data Portal | KAT7 |
| TCGA Data Portal | KAT7 |
| Broad Tumor Portal | KAT7 |
| OASIS Portal | KAT7 [ Somatic mutations - Copy number] |
| Cancer Gene: Census | KAT7 |
| Somatic Mutations in Cancer : COSMIC | KAT7 [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | KAT7 |
| Mutations and Diseases : HGMD | KAT7 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search KAT7 |
| DgiDB (Drug Gene Interaction Database) | KAT7 |
| DoCM (Curated mutations) | KAT7 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | KAT7 (select a term) |
| intoGen | KAT7 |
| Cancer3D | KAT7(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 609880 |
| Orphanet | |
| DisGeNET | KAT7 |
| Medgen | KAT7 |
| Genetic Testing Registry | KAT7
|
| NextProt | O95251 [Medical] |
| GENETests | KAT7 |
| Target Validation | KAT7 |
| Huge Navigator |
KAT7 [HugePedia] |
| ClinGen | KAT7 |
| Clinical trials, drugs, therapy |
|---|
| MyCancerGenome | KAT7 |
| Protein Interactions : CTD | |
| Pharm GKB Gene | PA134886407 |
| Pharos | O95251 |
| Clinical trial | KAT7 |
| Miscellaneous |
|---|
| canSAR (ICR) | KAT7 (select the gene name) |
| Harmonizome | KAT7 |
| DataMed Index | KAT7 |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 92 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| EVEX | KAT7 |
