KAZALD1 (Kazal type serine peptidase inhibitor domain 1)

2013-02-01  

Identity

HGNC
KAZALD1
LOCATION
10q24.31
LOCUSID
81621
ALIAS
BONO1,FKSG28,FKSG40,IGFBP-rP10
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 81621
MIM: 609208
HGNC: 25460
Ensembl: ENSG00000107821

Variants:

dbSNP: 81621
ClinVar: 81621
TCGA: ENSG00000107821
COSMIC: KAZALD1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000107821ENST00000370200Q96I82

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.69
263151102015Comprehensive molecular pathology analysis of small bowel adenocarcinoma reveals novel targets with potential for clinical utility.8
155555532004Role of a new member of IGFBP superfamily, IGFBP-rP10, in proliferation and differentiation of osteoblastic cells.6
228368052012Characterization of DNA hypermethylation in two cases of peritoneal mesothelioma.4
240025812013Epigenetic silencing of KAZALD1 confers a better prognosis and is associated with malignant transformation/progression in glioma.4
152618382004Bono1: a gene associated with regions of deposition of bone and dentine.3
152618382004Bono1: a gene associated with regions of deposition of bone and dentine.3

Citation

Dessen P

KAZALD1 (Kazal type serine peptidase inhibitor domain 1)

Atlas Genet Cytogenet Oncol Haematol. 2013-02-01

Online version: http://atlasgeneticsoncology.org/gene/53179/kazald1