Atlas of Genetics and Cytogenetics in Oncology and Haematology


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KCNE1B (potassium voltage-gated channel subfamily E regulatory subunit 1B)

Identity

Alias (NCBI)-
HGNC (Hugo) KCNE1B
LocusID (NCBI) 102723475
Atlas_Id 78766
Location 21p11.2  [Link to chromosome band 21p11]
Location_base_pair Starts at 7816677 and ends at 7829632 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KCNE1B   52280
Cards
Entrez_Gene (NCBI)KCNE1B  102723475  potassium voltage-gated channel subfamily E regulatory subunit 1B
Aliases
GeneCards (Weizmann)KCNE1B
Ensembl hg19 (Hinxton)ENSG00000276289 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000276289 [Gene_View]  ENSG00000276289 [Sequence]  chr21:7816677-7829632 [Contig_View]  KCNE1B [Vega]
ICGC DataPortalENSG00000276289
TCGA cBioPortalKCNE1B
AceView (NCBI)KCNE1B
Genatlas (Paris)KCNE1B
WikiGenes102723475
SOURCE (Princeton)KCNE1B
Genetics Home Reference (NIH)KCNE1B
Genomic and cartography
GoldenPath hg38 (UCSC)KCNE1B  -     chr21:7816677-7829632 -  21p11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KCNE1B  -     21p11.2   [Description]    (hg19-Feb_2009)
GoldenPathKCNE1B - 21p11.2 [CytoView hg19]  KCNE1B - 21p11.2 [CytoView hg38]
ImmunoBaseENSG00000276289
genome Data Viewer NCBIKCNE1B [Mapview hg19]  
Gene and transcription
Genbank (Entrez)-
RefSeq transcript (Entrez)NM_001330065 NM_001369869
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KCNE1B
Alternative Splicing GalleryENSG00000276289
Gene ExpressionKCNE1B [ NCBI-GEO ]   KCNE1B [ EBI - ARRAY_EXPRESS ]   KCNE1B [ SEEK ]   KCNE1B [ MEM ]
Gene Expression Viewer (FireBrowse)KCNE1B [ Firebrowse - Broad ]
GenevisibleExpression of KCNE1B in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)102723475
GTEX Portal (Tissue expression)KCNE1B
Human Protein AtlasENSG00000276289-KCNE1B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtA0A087WTH5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA0A087WTH5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA0A087WTH5
Splice isoforms : SwissVarA0A087WTH5
PhosPhoSitePlusA0A087WTH5
Domains : Interpro (EBI)K_chnl_KCNE    K_chnl_volt-dep_bsu_KCNE1   
Domain families : Pfam (Sanger)ISK_Channel (PF02060)   
Domain families : Pfam (NCBI)pfam02060   
Conserved Domain (NCBI)KCNE1B
DMDM Disease mutations102723475
Blocks (Seattle)KCNE1B
SuperfamilyA0A087WTH5
Human Protein Atlas [tissue]ENSG00000276289-KCNE1B [tissue]
Peptide AtlasA0A087WTH5
Protein Interaction databases
DIP (DOE-UCLA)A0A087WTH5
IntAct (EBI)A0A087WTH5
FunCoupENSG00000276289
BioGRIDKCNE1B
STRING (EMBL)KCNE1B
ZODIACKCNE1B
Ontologies - Pathways
QuickGOA0A087WTH5
Ontology : AmiGOdelayed rectifier potassium channel activity  voltage-gated potassium channel complex  potassium channel regulator activity  ion channel binding  regulation of ventricular cardiac muscle cell membrane repolarization  ventricular cardiac muscle cell action potential  membrane repolarization during action potential  regulation of heart rate by cardiac conduction  potassium ion export across plasma membrane  membrane repolarization during ventricular cardiac muscle cell action potential  negative regulation of delayed rectifier potassium channel activity  voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization  
Ontology : EGO-EBIdelayed rectifier potassium channel activity  voltage-gated potassium channel complex  potassium channel regulator activity  ion channel binding  regulation of ventricular cardiac muscle cell membrane repolarization  ventricular cardiac muscle cell action potential  membrane repolarization during action potential  regulation of heart rate by cardiac conduction  potassium ion export across plasma membrane  membrane repolarization during ventricular cardiac muscle cell action potential  negative regulation of delayed rectifier potassium channel activity  voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization  
NDEx NetworkKCNE1B
Atlas of Cancer Signalling NetworkKCNE1B
Wikipedia pathwaysKCNE1B
Orthology - Evolution
OrthoDB102723475
GeneTree (enSembl)ENSG00000276289
Phylogenetic Trees/Animal Genes : TreeFamKCNE1B
HOGENOMA0A087WTH5
Homologs : HomoloGeneKCNE1B
Homology/Alignments : Family Browser (UCSC)KCNE1B
Gene fusions - Rearrangements
Fusion : QuiverKCNE1B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKCNE1B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KCNE1B
dbVarKCNE1B
ClinVarKCNE1B
1000_GenomesKCNE1B 
Exome Variant ServerKCNE1B
GNOMAD BrowserENSG00000276289
Varsome BrowserKCNE1B
Genetic variants : HAPMAP102723475
Genomic Variants (DGV)KCNE1B [DGVbeta]
DECIPHERKCNE1B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKCNE1B 
Mutations
ICGC Data PortalKCNE1B 
TCGA Data PortalKCNE1B 
Broad Tumor PortalKCNE1B
OASIS PortalKCNE1B [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDKCNE1B
BioMutasearch KCNE1B
DgiDB (Drug Gene Interaction Database)KCNE1B
DoCM (Curated mutations)KCNE1B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KCNE1B (select a term)
intoGenKCNE1B
Cancer3DKCNE1B(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETKCNE1B
MedgenKCNE1B
Genetic Testing Registry KCNE1B
NextProtA0A087WTH5 [Medical]
TSGene102723475
GENETestsKCNE1B
Target ValidationKCNE1B
Huge Navigator KCNE1B [HugePedia]
snp3D : Map Gene to Disease102723475
BioCentury BCIQKCNE1B
ClinGenKCNE1B
Clinical trials, drugs, therapy
Protein Interactions : CTD102723475
Clinical trialKCNE1B
Miscellaneous
canSAR (ICR)KCNE1B (select the gene name)
HarmonizomeKCNE1B
DataMed IndexKCNE1B
Probes
Litterature
PubMed1 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKCNE1B
EVEXKCNE1B
GoPubMedKCNE1B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Thu Jul 16 15:59:38 CEST 2020

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