Identity
HGNC
LOCATION
2q11.1
LOCUSID
ALIAS
CSEN,DREAM,KCHIP3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 30818
MIM: 604662
HGNC: 15523
Ensembl: ENSG00000115041
Variants:
dbSNP: 30818
ClinVar: 30818
TCGA: ENSG00000115041
COSMIC: KCNIP3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000115041 | ENST00000295225 | Q9Y2W7 |
| ENSG00000115041 | ENST00000295225 | A0A024RE22 |
| ENSG00000115041 | ENST00000360990 | A0A0A0MRH3 |
| ENSG00000115041 | ENST00000468529 | Q9Y2W7 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Muscle contraction | REACTOME | R-HSA-397014 |
| Cardiac conduction | REACTOME | R-HSA-5576891 |
| Phase 1 - inactivation of fast Na+ channels | REACTOME | R-HSA-5576894 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37298129 | 2023 | Emerging Role of DREAM in Healthy Brain and Neurological Diseases. | 1 |
| 37978395 | 2023 | Loss of p53-DREAM-mediated repression of cell cycle genes as a driver of lymph node metastasis in head and neck cancer. | 1 |
| 37298129 | 2023 | Emerging Role of DREAM in Healthy Brain and Neurological Diseases. | 1 |
| 37978395 | 2023 | Loss of p53-DREAM-mediated repression of cell cycle genes as a driver of lymph node metastasis in head and neck cancer. | 1 |
| 34751735 | 2022 | Neutrophil DREAM promotes neutrophil recruitment in vascular inflammation. | 8 |
| 35066335 | 2022 | KCNIP3 silence promotes proliferation and epithelial-mesenchymal transition of papillary thyroid carcinoma through activating Wnt/β-catenin pathway. | 0 |
| 34751735 | 2022 | Neutrophil DREAM promotes neutrophil recruitment in vascular inflammation. | 8 |
| 35066335 | 2022 | KCNIP3 silence promotes proliferation and epithelial-mesenchymal transition of papillary thyroid carcinoma through activating Wnt/β-catenin pathway. | 0 |
| 33626321 | 2021 | PAF remodels the DREAM complex to bypass cell quiescence and promote lung tumorigenesis. | 23 |
| 33626321 | 2021 | PAF remodels the DREAM complex to bypass cell quiescence and promote lung tumorigenesis. | 23 |
| 32641494 | 2020 | Modulation of Kv4.2/KChIP3 interaction by the ceroid lipofuscinosis neuronal 3 protein CLN3. | 3 |
| 32641494 | 2020 | Modulation of Kv4.2/KChIP3 interaction by the ceroid lipofuscinosis neuronal 3 protein CLN3. | 3 |
| 30833638 | 2019 | Cyclin D-CDK4 relieves cooperative repression of proliferation and cell cycle gene expression by DREAM and RB. | 35 |
| 30833638 | 2019 | Cyclin D-CDK4 relieves cooperative repression of proliferation and cell cycle gene expression by DREAM and RB. | 35 |
| 30272559 | 2018 | KChIP3 coupled to Ca(2+) oscillations exerts a tonic brake on baseline mucin release in the colon. | 12 |
Citation
Dessen P
KCNIP3 (potassium voltage-gated channel interacting protein 3)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45968/kcnip3
