Identity
HGNC
LOCATION
2q24.1
LOCUSID
ALIAS
GIRK1,KGA,KIR3.1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3760
MIM: 601534
HGNC: 6264
Ensembl: ENSG00000162989
Variants:
dbSNP: 3760
ClinVar: 3760
TCGA: ENSG00000162989
COSMIC: KCNJ3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000162989 | ENST00000295101 | P48549 |
| ENSG00000162989 | ENST00000544049 | P48549 |
| ENSG00000162989 | ENST00000651198 | A0A494C0M7 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32541684 | 2020 | A constricted opening in Kir channels does not impede potassium conduction. | 10 |
| 32541684 | 2020 | A constricted opening in Kir channels does not impede potassium conduction. | 10 |
| 30764634 | 2019 | Mutant KCNJ3 and KCNJ5 Potassium Channels as Novel Molecular Targets in Bradyarrhythmias and Atrial Fibrillation. | 28 |
| 31848385 | 2019 | GIRK1 triggers multiple cancer-related pathways in the benign mammary epithelial cell line MCF10A. | 2 |
| 30764634 | 2019 | Mutant KCNJ3 and KCNJ5 Potassium Channels as Novel Molecular Targets in Bradyarrhythmias and Atrial Fibrillation. | 28 |
| 31848385 | 2019 | GIRK1 triggers multiple cancer-related pathways in the benign mammary epithelial cell line MCF10A. | 2 |
| 30240440 | 2018 | Gi/o-coupled muscarinic receptors co-localize with GIRK channel for efficient channel activation. | 9 |
| 30240440 | 2018 | Gi/o-coupled muscarinic receptors co-localize with GIRK channel for efficient channel activation. | 9 |
| 27074664 | 2016 | The GIRK1 subunit potentiates G protein activation of cardiac GIRK1/4 hetero-tetramers. | 12 |
| 27519272 | 2016 | Overexpression of KCNJ3 gene splice variants affects vital parameters of the malignant breast cancer cell line MCF-7 in an opposing manner. | 10 |
| 27835900 | 2016 | KCNJ3 is a new independent prognostic marker for estrogen receptor positive breast cancer patients. | 12 |
| 27074664 | 2016 | The GIRK1 subunit potentiates G protein activation of cardiac GIRK1/4 hetero-tetramers. | 12 |
| 27519272 | 2016 | Overexpression of KCNJ3 gene splice variants affects vital parameters of the malignant breast cancer cell line MCF-7 in an opposing manner. | 10 |
| 27835900 | 2016 | KCNJ3 is a new independent prognostic marker for estrogen receptor positive breast cancer patients. | 12 |
| 25599232 | 2015 | Variations in potassium channel genes are associated with distinct trajectories of persistent breast pain after breast cancer surgery. | 17 |
Citation
Dessen P
KCNJ3 (potassium inwardly rectifying channel subfamily J member 3)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45811/kcnj3
