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KCNJ5 (potassium voltage-gated channel subfamily J member 5)

Identity

Other namesCIR
GIRK4
KATP1
KIR3.4
LQT13
HGNC (Hugo) KCNJ5
LocusID (NCBI) 3762
Atlas_Id 46270
Location 11q24.3
Location_base_pair Starts at 128761313 and ends at 128787951 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
APLP2 (11q24.3) / KCNJ5 (11q24.3)APLP2 11q24.3 / KCNJ5 11q24.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KCNJ5   6266
Cards
Entrez_Gene (NCBI)KCNJ5  3762  potassium voltage-gated channel subfamily J member 5
AliasesCIR; GIRK4; KATP1; KIR3.4; 
LQT13
GeneCards (Weizmann)KCNJ5
Ensembl hg19 (Hinxton)ENSG00000120457 [Gene_View]  chr11:128761313-128787951 [Contig_View]  KCNJ5 [Vega]
Ensembl hg38 (Hinxton)ENSG00000120457 [Gene_View]  chr11:128761313-128787951 [Contig_View]  KCNJ5 [Vega]
ICGC DataPortalENSG00000120457
TCGA cBioPortalKCNJ5
AceView (NCBI)KCNJ5
Genatlas (Paris)KCNJ5
WikiGenes3762
SOURCE (Princeton)KCNJ5
Genomic and cartography
GoldenPath hg19 (UCSC)KCNJ5  -     chr11:128761313-128787951 +  11q24.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KCNJ5  -     11q24.3   [Description]    (hg38-Dec_2013)
EnsemblKCNJ5 - 11q24.3 [CytoView hg19]  KCNJ5 - 11q24.3 [CytoView hg38]
Mapping of homologs : NCBIKCNJ5 [Mapview hg19]  KCNJ5 [Mapview hg38]
OMIM600734   613485   613677   
Gene and transcription
Genbank (Entrez)AB690268 AK312837 BC069386 BC069482 BC069499
RefSeq transcript (Entrez)NM_000890
RefSeq genomic (Entrez)NC_000011 NC_018922 NG_023406 NT_033899 NW_004929381
Consensus coding sequences : CCDS (NCBI)KCNJ5
Cluster EST : UnigeneHs.632109 [ NCBI ]
CGAP (NCI)Hs.632109
Alternative Splicing GalleryENSG00000120457
Gene ExpressionKCNJ5 [ NCBI-GEO ]   KCNJ5 [ EBI - ARRAY_EXPRESS ]   KCNJ5 [ SEEK ]   KCNJ5 [ MEM ]
Gene Expression Viewer (FireBrowse)KCNJ5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3762
GTEX Portal (Tissue expression)KCNJ5
Protein : pattern, domain, 3D structure
UniProt/SwissProtP48544 (Uniprot)
NextProtP48544  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP48544
Splice isoforms : SwissVarP48544 (Swissvar)
PhosPhoSitePlusP48544
Domains : Interpro (EBI)Ig_E-set    K_chnl_inward-rec_Kir    K_chnl_inward-rec_Kir3.4    K_chnl_inward-rec_Kir_cyto   
Domain families : Pfam (Sanger)IRK (PF01007)   
Domain families : Pfam (NCBI)pfam01007   
DMDM Disease mutations3762
Blocks (Seattle)KCNJ5
SuperfamilyP48544
Human Protein AtlasENSG00000120457
Peptide AtlasP48544
HPRD09010
IPIIPI00298865   IPI00985408   IPI00981047   
Protein Interaction databases
DIP (DOE-UCLA)P48544
IntAct (EBI)P48544
FunCoupENSG00000120457
BioGRIDKCNJ5
STRING (EMBL)KCNJ5
ZODIACKCNJ5
Ontologies - Pathways
QuickGOP48544
Ontology : AmiGOinward rectifier potassium channel activity  protein binding  plasma membrane  potassium ion transport  voltage-gated potassium channel complex  external side of plasma membrane  potassium ion import  G-protein activated inward rectifier potassium channel activity  T-tubule  regulation of ion transmembrane transport  
Ontology : EGO-EBIinward rectifier potassium channel activity  protein binding  plasma membrane  potassium ion transport  voltage-gated potassium channel complex  external side of plasma membrane  potassium ion import  G-protein activated inward rectifier potassium channel activity  T-tubule  regulation of ion transmembrane transport  
Pathways : KEGGCircadian entrainment    Retrograde endocannabinoid signaling    Serotonergic synapse    Dopaminergic synapse    Estrogen signaling pathway    Morphine addiction   
NDEx Network
Atlas of Cancer Signalling NetworkKCNJ5
Wikipedia pathwaysKCNJ5
Orthology - Evolution
OrthoDB3762
GeneTree (enSembl)ENSG00000120457
Phylogenetic Trees/Animal Genes : TreeFamKCNJ5
Homologs : HomoloGeneKCNJ5
Homology/Alignments : Family Browser (UCSC)KCNJ5
Gene fusions - Rearrangements
Fusion: TCGAAPLP2 11q24.3 KCNJ5 11q24.3 BRCA
Polymorphisms : SNP, variants
NCBI Variation ViewerKCNJ5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KCNJ5
dbVarKCNJ5
ClinVarKCNJ5
1000_GenomesKCNJ5 
Exome Variant ServerKCNJ5
ExAC (Exome Aggregation Consortium)KCNJ5 (select the gene name)
Genetic variants : HAPMAP3762
Genomic Variants (DGV)KCNJ5 [DGVbeta]
Mutations
ICGC Data PortalKCNJ5 
TCGA Data PortalKCNJ5 
Broad Tumor PortalKCNJ5
OASIS PortalKCNJ5 [ Somatic mutations - Copy number]
Cancer Gene: CensusKCNJ5 
Somatic Mutations in Cancer : COSMICKCNJ5 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
LOVD (Leiden Open Variation Database)Zhejiang University Center for Genetic and Genomic Medicine (ZJU-CGGM)
BioMutasearch KCNJ5
DgiDB (Drug Gene Interaction Database)KCNJ5
DoCM (Curated mutations)KCNJ5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KCNJ5 (select a term)
intoGenKCNJ5
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)11:128761313-128787951  ENSG00000120457
CONAN: Copy Number AnalysisKCNJ5 
Mutations and Diseases : HGMDKCNJ5
OMIM600734    613485    613677   
MedgenKCNJ5
Genetic Testing Registry KCNJ5
NextProtP48544 [Medical]
TSGene3762
GENETestsKCNJ5
Huge Navigator KCNJ5 [HugePedia]
snp3D : Map Gene to Disease3762
BioCentury BCIQKCNJ5
ClinGenKCNJ5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3762
Chemical/Pharm GKB GenePA216
Clinical trialKCNJ5
Miscellaneous
canSAR (ICR)KCNJ5 (select the gene name)
Probes
Litterature
PubMed88 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKCNJ5
EVEXKCNJ5
GoPubMedKCNJ5
iHOPKCNJ5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat May 28 11:07:36 CEST 2016

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