Identity
HGNC
LOCATION
19q13.31
LOCUSID
ALIAS
DHS2,IK,IK1,IKCA1,KCA4,KCa3.1,SK4,hIKCa1,hKCa4,hSK4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3783
MIM: 602754
HGNC: 6293
Ensembl: ENSG00000104783
Variants:
dbSNP: 3783
ClinVar: 3783
TCGA: ENSG00000104783
COSMIC: KCNN4
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37968509 | 2024 | Overexpression of KCNN4 channels in principal neurons produces an anti-seizure effect without reducing their coding ability. | 0 |
| 38018635 | 2024 | A single coiled-coil domain mutation in hIKCa channel subunits disrupts preferential formation of heteromeric hSK1:hIKCa channels. | 1 |
| 38338693 | 2024 | The Gárdos Channel and Piezo1 Revisited: Comparison between Reticulocytes and Mature Red Blood Cells. | 0 |
| 38673845 | 2024 | Investigating the Impact of Electrostatic Interactions on Calmodulin Binding and Ca(2+)-Dependent Activation of the Calcium-Gated Potassium SK4 Channel. | 0 |
| 37968509 | 2024 | Overexpression of KCNN4 channels in principal neurons produces an anti-seizure effect without reducing their coding ability. | 0 |
| 38018635 | 2024 | A single coiled-coil domain mutation in hIKCa channel subunits disrupts preferential formation of heteromeric hSK1:hIKCa channels. | 1 |
| 38338693 | 2024 | The Gárdos Channel and Piezo1 Revisited: Comparison between Reticulocytes and Mature Red Blood Cells. | 0 |
| 38673845 | 2024 | Investigating the Impact of Electrostatic Interactions on Calmodulin Binding and Ca(2+)-Dependent Activation of the Calcium-Gated Potassium SK4 Channel. | 0 |
| 36571487 | 2023 | Pancreatic K(Ca)3.1 channels in health and disease. | 1 |
| 38134241 | 2023 | KCNN4 links PIEZO-dependent mechanotransduction to NLRP3 inflammasome activation. | 3 |
| 36571487 | 2023 | Pancreatic K(Ca)3.1 channels in health and disease. | 1 |
| 38134241 | 2023 | KCNN4 links PIEZO-dependent mechanotransduction to NLRP3 inflammasome activation. | 3 |
| 35805963 | 2022 | KCNN4 Promotes the Stemness Potentials of Liver Cancer Stem Cells by Enhancing Glucose Metabolism. | 9 |
| 35955737 | 2022 | Downregulation of IL-8 and IL-10 by the Activation of Ca(2+)-Activated K(+) Channel K(Ca)3.1 in THP-1-Derived M(2) Macrophages. | 6 |
| 35805963 | 2022 | KCNN4 Promotes the Stemness Potentials of Liver Cancer Stem Cells by Enhancing Glucose Metabolism. | 9 |
Citation
Dessen P
KCNN4 (potassium calcium-activated channel subfamily N member 4)
Atlas Genet Cytogenet Oncol Haematol. 2007-10-01
Online version: http://atlasgeneticsoncology.org/gene/49764/kcnn4
