KCTD5 (potassium channel tetramerization domain containing 5)

2019-08-01  

Identity

HGNC
KCTD5
LOCATION
16p13.3
LOCUSID
54442
ALIAS
-

Other Information

Locus ID:

NCBI: 54442
MIM: 611285
HGNC: 21423
Ensembl: ENSG00000167977

Variants:

dbSNP: 54442
ClinVar: 54442
TCGA: ENSG00000167977
COSMIC: KCTD5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000167977ENST00000301738Q9NXV2
ENSG00000167977ENST00000564195H3BSS5

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
193614492009Pentameric assembly of potassium channel tetramerization domain-containing protein 5.31
185731012008KCTD5, a putative substrate adaptor for cullin3 ubiquitin ligases.30
285625902017Genetic wiring maps of single-cell protein states reveal an off-switch for GPCR signalling.25
172394182007Identification of a cytoplasmic interaction partner of the large regulatory proteins Rep78/Rep68 of adeno-associated virus type 2 (AAV-2).4
261885162015Interactions of cullin3/KCTD5 complexes with both cytoplasmic and nuclear proteins: Evidence for a role in protein stabilization.2
297826462018Cullin3/KCTD5 induces monoubiquitination of ΔNp63α and impairs its activity.0

Citation

Dessen P

KCTD5 (potassium channel tetramerization domain containing 5)

Atlas Genet Cytogenet Oncol Haematol. 2019-08-01

Online version: http://atlasgeneticsoncology.org/gene/58060/kctd5