Identity
HGNC
LOCATION
Xq13.1
LOCUSID
ALIAS
KIF4,KIF4G1,MRX100
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 24137
MIM: 300521
HGNC: 13339
Ensembl: ENSG00000090889
Variants:
dbSNP: 24137
ClinVar: 24137
TCGA: ENSG00000090889
COSMIC: KIF4A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000090889 | ENST00000374403 | O95239 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36217900 | 2023 | KIF4A knockdown inhibits tumor progression and promotes chemo-sensitivity via induction of P21 in lung cancer cells. | 2 |
| 36468837 | 2023 | KIF4A promotes genomic stability and progression of endometrial cancer through regulation of TPX2 protein degradation. | 4 |
| 36849972 | 2023 | DEPDC1 and KIF4A synergistically inhibit the malignant biological behavior of osteosarcoma cells through Hippo signaling pathway. | 2 |
| 37039264 | 2023 | Knockdown of kinesin family member 4A inhibits cell proliferation, migration, and invasion while promoting apoptosis of urothelial bladder carcinoma cells. | 1 |
| 36217900 | 2023 | KIF4A knockdown inhibits tumor progression and promotes chemo-sensitivity via induction of P21 in lung cancer cells. | 2 |
| 36468837 | 2023 | KIF4A promotes genomic stability and progression of endometrial cancer through regulation of TPX2 protein degradation. | 4 |
| 36849972 | 2023 | DEPDC1 and KIF4A synergistically inhibit the malignant biological behavior of osteosarcoma cells through Hippo signaling pathway. | 2 |
| 37039264 | 2023 | Knockdown of kinesin family member 4A inhibits cell proliferation, migration, and invasion while promoting apoptosis of urothelial bladder carcinoma cells. | 1 |
| 35182680 | 2022 | EZH2 suppresses insulinoma development by epigenetically reducing KIF4A expression via H3K27me3 modification. | 1 |
| 35312737 | 2022 | The kinesin KIF4 mediates HBV/HDV entry through the regulation of surface NTCP localization and can be targeted by RXR agonists in vitro. | 3 |
| 35399116 | 2022 | KIF4A promotes tumor progression of bladder cancer via CXCL5 dependent myeloid-derived suppressor cells recruitment. | 3 |
| 35882623 | 2022 | Kif4A mediates resistance to neoadjuvant chemoradiotherapy in patients with advanced colorectal cancer via regulating DNA damage response. | 4 |
| 35926461 | 2022 | Length-dependent poleward flux of sister kinetochore fibers promotes chromosome alignment. | 7 |
| 36260268 | 2022 | Bioinformatic and Experimental Analyses Reveal That KIF4A Is a Biomarker of Therapeutic Sensitivity and Predicts Prognosis in Cervical Cancer Patients. | 1 |
| 35182680 | 2022 | EZH2 suppresses insulinoma development by epigenetically reducing KIF4A expression via H3K27me3 modification. | 1 |
Citation
Dessen P
KIF4A (kinesin family member 4A)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46090/kif4a
