KIR2DL1 (killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1)
2007-02-01 AffiliationIdentity
HGNC
LOCATION
19q13.42
LOCUSID
ALIAS
CD158A,KIR-K64,KIR221,KIR2DL3,NKAT,NKAT-1,NKAT1,p58.1
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3802
MIM: 604936
HGNC: 6329
Ensembl: ENSG00000125498
Variants:
dbSNP: 3802
ClinVar: 3802
TCGA: ENSG00000125498
COSMIC: KIR2DL1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000125498 | ENST00000291633 | P43626 |
| ENSG00000125498 | ENST00000336077 | Q6H2H3 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38240527 | 2024 | KIR2DS1 and KIR2DL1-C245 Dominantly Repress NK Cell Degranulation Triggered by Monoclonal or Bispecific Antibodies, whereas Education by Uptuning Inhibitory Killer Ig-related Receptors Exerts No Advantage in Ab-dependent Cellular Cytotoxicity. | 0 |
| 38262874 | 2024 | Activating KIR/HLA-I combinations as a risk factor of adult B-ALL. | 0 |
| 38240527 | 2024 | KIR2DS1 and KIR2DL1-C245 Dominantly Repress NK Cell Degranulation Triggered by Monoclonal or Bispecific Antibodies, whereas Education by Uptuning Inhibitory Killer Ig-related Receptors Exerts No Advantage in Ab-dependent Cellular Cytotoxicity. | 0 |
| 38262874 | 2024 | Activating KIR/HLA-I combinations as a risk factor of adult B-ALL. | 0 |
| 37801092 | 2023 | The KIR2DL1 intermediate upstream element participates in gene activation. | 0 |
| 37801092 | 2023 | The KIR2DL1 intermediate upstream element participates in gene activation. | 0 |
| 36713400 | 2022 | Uterine NK cells underexpress KIR2DL1/S1 and LILRB1 in reproductive failure. | 2 |
| 36713400 | 2022 | Uterine NK cells underexpress KIR2DL1/S1 and LILRB1 in reproductive failure. | 2 |
| 33906789 | 2021 | Lack of association of KIR2DL1-R(245) and KIR2DL1-C(245) with HIV-1 control in black South Africans with HLA-C2. | 0 |
| 33906789 | 2021 | Lack of association of KIR2DL1-R(245) and KIR2DL1-C(245) with HIV-1 control in black South Africans with HLA-C2. | 0 |
| 32983108 | 2020 | Single Nucleotide Polymorphism in KIR2DL1 Is Associated With HLA-C Expression in Global Populations. | 11 |
| 32983108 | 2020 | Single Nucleotide Polymorphism in KIR2DL1 Is Associated With HLA-C Expression in Global Populations. | 11 |
| 30698860 | 2019 | Differential contribution of education through KIR2DL1, KIR2DL3, and KIR3DL1 to antibody-dependent (AD) NK cell activation and ADCC. | 9 |
| 31519864 | 2019 | KIR Polymorphism Modulates the Size of the Adaptive NK Cell Pool in Human Cytomegalovirus-Infected Individuals. | 17 |
| 30698860 | 2019 | Differential contribution of education through KIR2DL1, KIR2DL3, and KIR3DL1 to antibody-dependent (AD) NK cell activation and ADCC. | 9 |
Citation
Dessen P
KIR2DL1 (killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43665/kir2dl1
