KIR2DS1 (killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 1)

2012-09-01  

Identity

HGNC
KIR2DS1
LOCATION
19q13.42
LOCUSID
3806
ALIAS
CD158H,CD158a,p50.1

Other Information

Locus ID:

NCBI: 3806
MIM: 604952
HGNC: 6333

Variants:

dbSNP: 3806
ClinVar: 3806
COSMIC: KIR2DS1

Pathways

PathwaySourceExternal ID
Antigen processing and presentationKEGGko04612
Natural killer cell mediated cytotoxicityKEGGko04650
Antigen processing and presentationKEGGhsa04612
Natural killer cell mediated cytotoxicityKEGGhsa04650
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellREACTOMER-HSA-198933

References

Pubmed IDYearTitleCitations
189459622009Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia.166
229313142012HLA-C-dependent prevention of leukemia relapse by donor activating KIR2DS1.151
161413292005Recognition of peptide-MHC class I complexes by activating killer immunoglobulin-like receptors.118
240913232013Maternal uterine NK cell-activating receptor KIR2DS1 enhances placentation.72
182636392008Association of maternal killer-cell immunoglobulin-like receptors and parental HLA-C genotypes with recurrent miscarriage.69
199342972009KIR and HLA genotypes are associated with disease progression and survival following autologous hematopoietic stem cell transplantation for high-risk neuroblastoma.50
153105282004Gene for the activating natural killer cell receptor, KIR2DS1, is associated with susceptibility to psoriasis vulgaris.38
153105282004Gene for the activating natural killer cell receptor, KIR2DS1, is associated with susceptibility to psoriasis vulgaris.38
247784452014Maternal KIR in combination with paternal HLA-C2 regulate human birth weight.38
213550852011Natural killer cells expressing the KIR2DS1-activating receptor efficiently kill T-cell blasts and dendritic cells: implications in haploidentical HSCT.35

Citation

Dessen P

KIR2DS1 (killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 1)

Atlas Genet Cytogenet Oncol Haematol. 2012-09-01

Online version: http://atlasgeneticsoncology.org/gene/52890/kir2ds1