KIR2DS4 (killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4)
2007-02-01 AffiliationIdentity
HGNC
LOCATION
19q13.42
LOCUSID
ALIAS
CD158I,KIR-2DS4,KIR1D,KIR412,KKA3,NKAT-8,NKAT8
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3809
MIM: 604955
HGNC: 6336
Ensembl: ENSG00000221957
Variants:
dbSNP: 3809
ClinVar: 3809
TCGA: ENSG00000221957
COSMIC: KIR2DS4
RNA/Proteins
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA450428 | methotrexate | Chemical | MultilinkAnnotation | associated | 25069714 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38387251 | 2024 | Evaluation of the genetic diversity of KIR genes in patients with endometrial cancer. | 0 |
| 38387251 | 2024 | Evaluation of the genetic diversity of KIR genes in patients with endometrial cancer. | 0 |
| 37150297 | 2023 | KIR2DS4 and Its Variant KIR1D in KIR-AA Genotype Donors Showed Differential Survival Impact in Patients with Lymphoid Disease after HLA-Matched Unrelated Hematopoietic Stem Cell Transplantation. | 0 |
| 37150297 | 2023 | KIR2DS4 and Its Variant KIR1D in KIR-AA Genotype Donors Showed Differential Survival Impact in Patients with Lymphoid Disease after HLA-Matched Unrelated Hematopoietic Stem Cell Transplantation. | 0 |
| 34929414 | 2022 | Association of KIR gene polymorphisms with COVID-19 disease. | 14 |
| 34929414 | 2022 | Association of KIR gene polymorphisms with COVID-19 disease. | 14 |
| 31751561 | 2020 | KIR2DS4, KIR2DL2, and KIR2DS4del are linked with basaloid tumors, lymph node metastasis, advanced stage and metastatic risk in head and neck squamous cell carcinoma. | 3 |
| 31899050 | 2020 | Positive association of Bx genotype, KIR2L5, KIR2DS5 and full-length KIR2DS4 with the risk of meningioma. | 3 |
| 32422377 | 2020 | Natural killer cell receptor variants and chronic hepatitis B virus infection in the Vietnamese population. | 6 |
| 32594584 | 2020 | The impact of donor full-length KIR2DS4 in the development of acute and chronic GVHD after unrelated allogeneic HSCT. | 1 |
| 31751561 | 2020 | KIR2DS4, KIR2DL2, and KIR2DS4del are linked with basaloid tumors, lymph node metastasis, advanced stage and metastatic risk in head and neck squamous cell carcinoma. | 3 |
| 31899050 | 2020 | Positive association of Bx genotype, KIR2L5, KIR2DS5 and full-length KIR2DS4 with the risk of meningioma. | 3 |
| 32422377 | 2020 | Natural killer cell receptor variants and chronic hepatitis B virus infection in the Vietnamese population. | 6 |
| 32594584 | 2020 | The impact of donor full-length KIR2DS4 in the development of acute and chronic GVHD after unrelated allogeneic HSCT. | 1 |
| 30508863 | 2019 | Acute Exercise Increases the Expression of KIR2DS4 by Promoter Demethylation in NK Cells. | 5 |
Citation
Dessen P
KIR2DS4 (killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46006/kir2ds4
