KIR3DL3 (killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3)

2014-11-01  

Identity

HGNC
LOCATION
19q13.42
LOCUSID
ALIAS
CD158Z,KIR3DL7,KIR44,KIRC1

Other Information

Locus ID:

NCBI: 115653
MIM: 610095
HGNC: 16312
Ensembl: ENSG00000242019

Variants:

dbSNP: 115653
ClinVar: 115653
TCGA: ENSG00000242019
COSMIC: KIR3DL3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000242019ENST00000291860A0A0B4J1R5

Expression (GTEx)

0
1

Pathways

PathwaySourceExternal ID
Antigen processing and presentationKEGGko04612
Antigen processing and presentationKEGGhsa04612

References

Pubmed IDYearTitleCitations
189459622009Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia.166
208784002010Association of KIR2DS1 and KIR2DS3 with fatal outcome in Ebola virus infection.32
198465352010Effect of killer immunoglobulin-like receptors in the response to combined treatment in patients with chronic hepatitis C virus infection.31
190322282008Natural killer cell receptor repertoire and their ligands, and the risk of CMV infection after kidney transplantation.22
198611442010Activating killer cell immunoglobulin-like receptors 3DS1 and 2DS1 protect against developing the severe form of recurrent respiratory papillomatosis.22
203318342010Report from the killer immunoglobulin-like receptor (KIR) anthropology component of the 15th International Histocompatibility Workshop: worldwide variation in the KIR loci and further evidence for the co-evolution of KIR and HLA.22
157783732005Three structurally and functionally divergent kinds of promoters regulate expression of clonally distributed killer cell Ig-like receptors (KIR), of KIR2DL4, and of KIR3DL3.21
196300742009Killer immunoglobulin-like receptor ligand HLA-Bw4 protects against multiple sclerosis.20
158962042005Distribution of killer cell immunoglobulin-like receptor genes in the Chinese Han population.19
163919392006Molecular characterization of KIR3DL3.17

Citation

Dessen P

KIR3DL3 (killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64935/kir3dl3