| Nomenclature |
|---|
| HGNC (Hugo) | KLF10 11810 |
| LRG (Locus Reference Genomic) | LRG_758 |
| Cards |
|---|
| Entrez_Gene (NCBI) | KLF10 7071 Kruppel like factor 10 |
| Aliases | EGR-alpha; EGRA; TIEG; TIEG1 |
| GeneCards (Weizmann) | KLF10 |
| Ensembl hg19 (Hinxton) | ENSG00000155090 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000155090 [Gene_View] ENSG00000155090 [Sequence] chr8:102648777-102655902 [Contig_View] KLF10 [Vega] |
| ICGC DataPortal | ENSG00000155090 |
| TCGA cBioPortal | KLF10 |
| AceView (NCBI) | KLF10 |
| Genatlas (Paris) | KLF10 |
| WikiGenes | 7071 |
| SOURCE (Princeton) | KLF10 |
| Genetics Home Reference (NIH) | KLF10 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | KLF10 - chr8:102648777-102655902 - 8q22.3 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | KLF10 - 8q22.3 [Description] (hg19-Feb_2009) |
| GoldenPath | KLF10 - 8q22.3 [CytoView hg19] KLF10 - 8q22.3 [CytoView hg38] |
| ImmunoBase | ENSG00000155090 |
| Mapping of homologs : NCBI | KLF10 [Mapview hg19] KLF10 [Mapview hg38] |
| OMIM | 601878 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AK312894 BC011538 BC095399 BI560615 BQ575313 |
| RefSeq transcript (Entrez) | NM_001032282 NM_005655 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | KLF10 |
| Cluster EST : Unigene | Hs.435001 [ NCBI ] |
| CGAP (NCI) | Hs.435001 |
| Alternative Splicing Gallery | ENSG00000155090 |
| Gene Expression | KLF10 [ NCBI-GEO ] KLF10 [ EBI - ARRAY_EXPRESS ]
KLF10 [ SEEK ] KLF10 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | KLF10 [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 7071 |
| GTEX Portal (Tissue expression) | KLF10 |
| Human Protein Atlas | ENSG00000155090-KLF10 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | Q13118 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | Q13118 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | Q13118 |
| Splice isoforms : SwissVar | Q13118 |
| PhosPhoSitePlus | Q13118 |
| Domaine pattern : Prosite (Expaxy) | ZINC_FINGER_C2H2_1 (PS00028) ZINC_FINGER_C2H2_2 (PS50157) |
| Domains : Interpro (EBI) | Znf_C2H2_sf Znf_C2H2_type |
| Domain families : Pfam (Sanger) | |
| Domain families : Pfam (NCBI) | |
| Domain families : Smart (EMBL) | ZnF_C2H2 (SM00355) |
| Conserved Domain (NCBI) | KLF10 |
| DMDM Disease mutations | 7071 |
| Blocks (Seattle) | KLF10 |
| PDB (RSDB) | 2EPA |
| PDB Europe | 2EPA |
| PDB (PDBSum) | 2EPA |
| PDB (IMB) | 2EPA |
| Structural Biology KnowledgeBase | 2EPA |
| SCOP (Structural Classification of Proteins) | 2EPA |
| CATH (Classification of proteins structures) | 2EPA |
| Superfamily | Q13118 |
| Human Protein Atlas [tissue] | ENSG00000155090-KLF10 [tissue] |
| Peptide Atlas | Q13118 |
| HPRD | 03527 |
| IPI | IPI00011863 IPI00651766 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | Q13118 |
| IntAct (EBI) | Q13118 |
| FunCoup | ENSG00000155090 |
| BioGRID | KLF10 |
| STRING (EMBL) | KLF10 |
| ZODIAC | KLF10 |
| Ontologies - Pathways |
|---|
| QuickGO | Q13118 |
| Ontology : AmiGO | negative regulation of transcription by RNA polymerase II RNA polymerase II proximal promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific core promoter sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity protein binding nucleus nucleus regulation of transcription by RNA polymerase II cell-cell signaling circadian rhythm negative regulation of cell proliferation cellular response to starvation bone mineralization somatic stem cell population maintenance regulation of circadian rhythm positive regulation of osteoclast differentiation negative regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II metal ion binding cellular response to peptide |
| Ontology : EGO-EBI | negative regulation of transcription by RNA polymerase II RNA polymerase II proximal promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific core promoter sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity protein binding nucleus nucleus regulation of transcription by RNA polymerase II cell-cell signaling circadian rhythm negative regulation of cell proliferation cellular response to starvation bone mineralization somatic stem cell population maintenance regulation of circadian rhythm positive regulation of osteoclast differentiation negative regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II metal ion binding cellular response to peptide |
| NDEx Network | KLF10 |
| Atlas of Cancer Signalling Network | KLF10 |
| Wikipedia pathways | KLF10 |
| Orthology - Evolution |
|---|
| OrthoDB | 7071 |
| GeneTree (enSembl) | ENSG00000155090 |
| Phylogenetic Trees/Animal Genes : TreeFam | KLF10 |
| HOGENOM | Q13118 |
| Homologs : HomoloGene | KLF10 |
| Homology/Alignments : Family Browser (UCSC) | KLF10 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Mitelman | ARHGEF7/KLF10 [13q34/8q22.3] [t(8;13)(q22;q34)] |
| Fusion Portal | ARHGEF7 13q34 KLF10 8q22.3 BLCA |
| Fusion : Quiver | KLF10 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | KLF10 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | KLF10 |
| dbVar | KLF10 |
| ClinVar | KLF10 |
| 1000_Genomes | KLF10 |
| Exome Variant Server | KLF10 |
| ExAC (Exome Aggregation Consortium) | ENSG00000155090 |
| GNOMAD Browser | ENSG00000155090 |
| Varsome Browser | KLF10 |
| Genetic variants : HAPMAP | 7071 |
| Genomic Variants (DGV) | KLF10 [DGVbeta] |
| DECIPHER | KLF10 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | KLF10 |
| Mutations |
|---|
| ICGC Data Portal | KLF10 |
| TCGA Data Portal | KLF10 |
| Broad Tumor Portal | KLF10 |
| OASIS Portal | KLF10 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | KLF10 [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | KLF10 |
| Mutations and Diseases : HGMD | KLF10 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search KLF10 |
| DgiDB (Drug Gene Interaction Database) | KLF10 |
| DoCM (Curated mutations) | KLF10 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | KLF10 (select a term) |
| intoGen | KLF10 |
| Cancer3D | KLF10(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 601878 |
| Orphanet | |
| DisGeNET | KLF10 |
| Medgen | KLF10 |
| Genetic Testing Registry | KLF10
|
| NextProt | Q13118 [Medical] |
| TSGene | 7071 |
| GENETests | KLF10 |
| Target Validation | KLF10 |
| Huge Navigator |
KLF10 [HugePedia] |
| snp3D : Map Gene to Disease | 7071 |
| BioCentury BCIQ | KLF10 |
| ClinGen | KLF10 |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 7071 |
| Chemical/Pharm GKB Gene | PA36517 |
| Clinical trial | KLF10 |
| Miscellaneous |
|---|
| canSAR (ICR) | KLF10 (select the gene name) |
| DataMed Index | KLF10 |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 81 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | KLF10 |
| EVEX | KLF10 |
| GoPubMed | KLF10 |
| iHOP | KLF10 |
