Identity
HGNC
LOCATION
13q22.1
LOCUSID
ALIAS
AP-2rep,AP2REP,HSPC122
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 11278
MIM: 607531
HGNC: 6346
Ensembl: ENSG00000118922
Variants:
dbSNP: 11278
ClinVar: 11278
TCGA: ENSG00000118922
COSMIC: KLF12
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000118922 | ENST00000377669 | Q9Y4X4 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37156774 | 2023 | KLF12 promotes the proliferation of breast cancer cells by reducing the transcription of p21 in a p53-dependent and p53-independent manner. | 3 |
| 37290172 | 2023 | MiR-17-5p promoter methylation regulated by DNA methyltransferase 3 beta (DNMT3B) expedites endometriosis via the Krüppel-like factor 12 (KLF12)/Wnt/β-catenin axis. | 1 |
| 37543362 | 2023 | Krüppel-like factor 12 regulates aging ovarian granulosa cell apoptosis by repressing SPHK1 transcription and sphingosine-1-phosphate (S1P) production. | 0 |
| 37606530 | 2023 | KLF12 transcriptionally regulates PD-L1 expression in non-small cell lung cancer. | 0 |
| 37698263 | 2023 | Circ_0084188 promotes colorectal cancer progression by sponging miR-654-3p and regulating kruppel-like factor 12. | 1 |
| 37156774 | 2023 | KLF12 promotes the proliferation of breast cancer cells by reducing the transcription of p21 in a p53-dependent and p53-independent manner. | 3 |
| 37290172 | 2023 | MiR-17-5p promoter methylation regulated by DNA methyltransferase 3 beta (DNMT3B) expedites endometriosis via the Krüppel-like factor 12 (KLF12)/Wnt/β-catenin axis. | 1 |
| 37543362 | 2023 | Krüppel-like factor 12 regulates aging ovarian granulosa cell apoptosis by repressing SPHK1 transcription and sphingosine-1-phosphate (S1P) production. | 0 |
| 37606530 | 2023 | KLF12 transcriptionally regulates PD-L1 expression in non-small cell lung cancer. | 0 |
| 37698263 | 2023 | Circ_0084188 promotes colorectal cancer progression by sponging miR-654-3p and regulating kruppel-like factor 12. | 1 |
| 36272152 | 2022 | MicroRNA-650 suppresses KLF12 expression to regulate growth and metastasis of human ovarian cancer cells. | 2 |
| 36272152 | 2022 | MicroRNA-650 suppresses KLF12 expression to regulate growth and metastasis of human ovarian cancer cells. | 2 |
| 33279628 | 2021 | Krüppel-like factor 12 suppresses bladder cancer growth through transcriptionally inhibition of enolase 2. | 10 |
| 34117589 | 2021 | Knockdown of circ_0075503 suppresses cell migration and invasion by regulating miR-15a-5p and KLF12 in endometriosis. | 5 |
| 34461926 | 2021 | Circ-RNF111 aggravates the malignancy of gastric cancer through miR-876-3p-dependent regulation of KLF12. | 9 |
Citation
Dessen P
KLF12 (Kruppel like factor 12)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/41073/klf12
