Identity
HGNC
LOCATION
3q21.1
LOCUSID
ALIAS
IPOA5,NPI-1,RCH2,SRP1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3836
MIM: 600686
HGNC: 6394
Ensembl: ENSG00000114030
Variants:
dbSNP: 3836
ClinVar: 3836
TCGA: ENSG00000114030
COSMIC: KPNA1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37038032 | 2023 | Karyopherin Subunit Alpha 1 Enhances the Malignant Behaviors of Colon Cancer Cells via Promoting Nuclear Factor-κB p65 Nuclear Translocation. | 2 |
| 37038032 | 2023 | Karyopherin Subunit Alpha 1 Enhances the Malignant Behaviors of Colon Cancer Cells via Promoting Nuclear Factor-κB p65 Nuclear Translocation. | 2 |
| 35991835 | 2022 | Decreased Expression of Karyopherin-α 1 is Related to the Malignant Degree of Cervical Cancer and is Critical for the Proliferation of Hela Cells. | 5 |
| 35991835 | 2022 | Decreased Expression of Karyopherin-α 1 is Related to the Malignant Degree of Cervical Cancer and is Critical for the Proliferation of Hela Cells. | 5 |
| 33439253 | 2021 | Antivirals that target the host IMPα/β1-virus interface. | 21 |
| 34195786 | 2021 | Structural and calorimetric studies reveal specific determinants for the binding of a high-affinity NLS to mammalian importin-alpha. | 0 |
| 34709749 | 2021 | KPNA1 regulates nuclear import of NCOR2 splice variant BQ323636.1 to confer tamoxifen resistance in breast cancer. | 8 |
| 33439253 | 2021 | Antivirals that target the host IMPα/β1-virus interface. | 21 |
| 34195786 | 2021 | Structural and calorimetric studies reveal specific determinants for the binding of a high-affinity NLS to mammalian importin-alpha. | 0 |
| 34709749 | 2021 | KPNA1 regulates nuclear import of NCOR2 splice variant BQ323636.1 to confer tamoxifen resistance in breast cancer. | 8 |
| 29304174 | 2018 | Importin α1 is required for nuclear import of herpes simplex virus proteins and capsid assembly in fibroblasts and neurons. | 24 |
| 29304174 | 2018 | Importin α1 is required for nuclear import of herpes simplex virus proteins and capsid assembly in fibroblasts and neurons. | 24 |
| 28455446 | 2017 | Enterovirus 71 suppresses interferon responses by blocking Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling through inducing karyopherin-α1 degradation. | 42 |
| 28864541 | 2017 | Karyopherins regulate nuclear pore complex barrier and transport function. | 45 |
| 28455446 | 2017 | Enterovirus 71 suppresses interferon responses by blocking Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling through inducing karyopherin-α1 degradation. | 42 |
Citation
Dessen P
KPNA1 (karyopherin subunit alpha 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/41096/kpna1
