Identity
HGNC
LOCATION
17q21.2
LOCUSID
ALIAS
CK14,EBS3,EBS4,K14,NFJ
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3861
MIM: 148066
HGNC: 6416
Ensembl: ENSG00000186847
Variants:
dbSNP: 3861
ClinVar: 3861
TCGA: ENSG00000186847
COSMIC: KRT14
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000186847 | ENST00000167586 | P02533 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Developmental Biology | REACTOME | R-HSA-1266738 |
| Keratinization | REACTOME | R-HSA-6805567 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38474236 | 2024 | EBS in Children with De Novo Pathogenic Variants Disturbing Krt14. | 0 |
| 38580989 | 2024 | Epidermolysis Bullosa: Two rare case reports of COL7A1 and EBS-GEN SEV KRT14 variants with review of literature. | 0 |
| 38474236 | 2024 | EBS in Children with De Novo Pathogenic Variants Disturbing Krt14. | 0 |
| 38580989 | 2024 | Epidermolysis Bullosa: Two rare case reports of COL7A1 and EBS-GEN SEV KRT14 variants with review of literature. | 0 |
| 35031308 | 2022 | Keratin 14 Degradation and Aging in Epidermolysis Bullosa Simplex due to KLHL24 Gain-of-Function Variants. | 4 |
| 36446780 | 2022 | EZH2-H3K27me3 mediated KRT14 upregulation promotes TNBC peritoneal metastasis. | 18 |
| 35031308 | 2022 | Keratin 14 Degradation and Aging in Epidermolysis Bullosa Simplex due to KLHL24 Gain-of-Function Variants. | 4 |
| 36446780 | 2022 | EZH2-H3K27me3 mediated KRT14 upregulation promotes TNBC peritoneal metastasis. | 18 |
| 34509171 | 2021 | Molecular origin of the effects of mutation on the structure and mechanical properties of human epithelial keratin K5/K14. | 1 |
| 34830328 | 2021 | Keratins as an Inflammation Trigger Point in Epidermolysis Bullosa Simplex. | 7 |
| 34962936 | 2021 | A mathematical model for the dependence of keratin aggregate formation on the quantity of mutant keratin expressed in EGFP-K14 R125P keratinocytes. | 0 |
| 34509171 | 2021 | Molecular origin of the effects of mutation on the structure and mechanical properties of human epithelial keratin K5/K14. | 1 |
| 34830328 | 2021 | Keratins as an Inflammation Trigger Point in Epidermolysis Bullosa Simplex. | 7 |
| 34962936 | 2021 | A mathematical model for the dependence of keratin aggregate formation on the quantity of mutant keratin expressed in EGFP-K14 R125P keratinocytes. | 0 |
| 31995743 | 2020 | Structure-Function Analyses of a Keratin Heterotypic Complex Identify Specific Keratin Regions Involved in Intermediate Filament Assembly. | 10 |
Citation
Dessen P
KRT14 (keratin 14)
Atlas Genet Cytogenet Oncol Haematol. 2008-05-01
Online version: http://atlasgeneticsoncology.org/gene/50134/krt14
