Identity
HGNC
LOCATION
12q13.13
LOCUSID
ALIAS
CK5,DDD,DDD1,EBS2,K5,KRT5A
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3852
MIM: 148040
HGNC: 6442
Ensembl: ENSG00000186081
Variants:
dbSNP: 3852
ClinVar: 3852
TCGA: ENSG00000186081
COSMIC: KRT5
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Developmental Biology | REACTOME | R-HSA-1266738 |
| Keratinization | REACTOME | R-HSA-6805567 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36239561 | 2023 | Clinicopathological features of cytokeratin 5-positive pulmonary adenocarcinoma. | 1 |
| 36809573 | 2023 | KRT5 mutation regulate melanin metabolism through notch signalling pathway between keratinocytes and melanocytes. | 2 |
| 37212698 | 2023 | Keratin 5 in Lung Cancer Specimens: Comparison of Four Antibody Clones and KRT5 mRNA-ISH. | 0 |
| 37758700 | 2023 | Lung extracellular matrix modulates KRT5(+) basal cell activity in pulmonary fibrosis. | 4 |
| 36239561 | 2023 | Clinicopathological features of cytokeratin 5-positive pulmonary adenocarcinoma. | 1 |
| 36809573 | 2023 | KRT5 mutation regulate melanin metabolism through notch signalling pathway between keratinocytes and melanocytes. | 2 |
| 37212698 | 2023 | Keratin 5 in Lung Cancer Specimens: Comparison of Four Antibody Clones and KRT5 mRNA-ISH. | 0 |
| 37758700 | 2023 | Lung extracellular matrix modulates KRT5(+) basal cell activity in pulmonary fibrosis. | 4 |
| 35527047 | 2022 | Cytokeratin 5/6 expression in pT1 bladder cancer predicts intravesical recurrence in patients treated with bacillus Calmette-Guérin instillation. | 0 |
| 35639459 | 2022 | Cytokeratins 5 and 17 Maintain an Aggressive Epithelial State in Basal-Like Breast Cancer. | 2 |
| 35527047 | 2022 | Cytokeratin 5/6 expression in pT1 bladder cancer predicts intravesical recurrence in patients treated with bacillus Calmette-Guérin instillation. | 0 |
| 35639459 | 2022 | Cytokeratins 5 and 17 Maintain an Aggressive Epithelial State in Basal-Like Breast Cancer. | 2 |
| 32989862 | 2021 | Severe skin fragility with postnatal lethal outcome due to a biallelic KRT5 mutation. | 0 |
| 33435173 | 2021 | Comprehensive Gene Expression Analyses of Immunohistochemically Defined Subgroups of Muscle-Invasive Urinary Bladder Urothelial Carcinoma. | 7 |
| 34509171 | 2021 | Molecular origin of the effects of mutation on the structure and mechanical properties of human epithelial keratin K5/K14. | 1 |
Citation
Dessen P
KRT5 (keratin 5)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45642/krt5
