Identity
HGNC
LOCATION
12q13.13
LOCUSID
ALIAS
HB1,Hb-1,K81,KRTHB1,MLN137,ghHkb1,hHAKB2-1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3887
MIM: 602153
HGNC: 6458
Ensembl: ENSG00000205426
Variants:
dbSNP: 3887
ClinVar: 3887
TCGA: ENSG00000205426
COSMIC: KRT81
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000205426 | ENST00000327741 | Q14533 |
| ENSG00000205426 | ENST00000615839 | A0A087X106 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Developmental Biology | REACTOME | R-HSA-1266738 |
| Keratinization | REACTOME | R-HSA-6805567 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37949677 | 2024 | Ectopic Expression of a Truncated Isoform of Hair Keratin 81 in Breast Cancer Alters Biophysical Characteristics to Promote Metastatic Propensity. | 1 |
| 37949677 | 2024 | Ectopic Expression of a Truncated Isoform of Hair Keratin 81 in Breast Cancer Alters Biophysical Characteristics to Promote Metastatic Propensity. | 1 |
| 34591651 | 2021 | KRT81 Knockdown Inhibits Malignant Progression of Melanoma Through Regulating Interleukin-8. | 11 |
| 34591651 | 2021 | KRT81 Knockdown Inhibits Malignant Progression of Melanoma Through Regulating Interleukin-8. | 11 |
| 32678982 | 2020 | A Polymorphism at the microRNA Binding Site in the 3' Untranslated Region of KRT81 Is Associated with Breast Cancer. | 4 |
| 32678982 | 2020 | A Polymorphism at the microRNA Binding Site in the 3' Untranslated Region of KRT81 Is Associated with Breast Cancer. | 4 |
| 29101303 | 2018 | Pancreatic Ductal Adenocarcinoma Subtyping Using the Biomarkers Hepatocyte Nuclear Factor-1A and Cytokeratin-81 Correlates with Outcome and Treatment Response. | 48 |
| 29101303 | 2018 | Pancreatic Ductal Adenocarcinoma Subtyping Using the Biomarkers Hepatocyte Nuclear Factor-1A and Cytokeratin-81 Correlates with Outcome and Treatment Response. | 48 |
| 28405679 | 2017 | Hair keratin KRT81 is expressed in normal and breast cancer cells and contributes to their invasiveness. | 15 |
| 28405679 | 2017 | Hair keratin KRT81 is expressed in normal and breast cancer cells and contributes to their invasiveness. | 15 |
| 25557232 | 2015 | Novel KRT83 and KRT86 mutations associated with monilethrix. | 5 |
| 25716425 | 2015 | A genetic variation in microRNA target site of KRT81 gene is associated with survival in early-stage non-small-cell lung cancer. | 12 |
| 25557232 | 2015 | Novel KRT83 and KRT86 mutations associated with monilethrix. | 5 |
| 25716425 | 2015 | A genetic variation in microRNA target site of KRT81 gene is associated with survival in early-stage non-small-cell lung cancer. | 12 |
| 24530479 | 2014 | A miR-SNP of the KRT81 gene is associated with the prognosis of non-Hodgkin's lymphoma. | 6 |
Citation
Dessen P
KRT81 (keratin 81)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45888/krt81
