KRT81 (keratin 81)

2007-02-01  

Identity

HGNC
LOCATION
12q13.13
LOCUSID
ALIAS
HB1,Hb-1,K81,KRTHB1,MLN137,ghHkb1,hHAKB2-1
FUSION GENES

Other Information

Locus ID:

NCBI: 3887
MIM: 602153
HGNC: 6458
Ensembl: ENSG00000205426

Variants:

dbSNP: 3887
ClinVar: 3887
TCGA: ENSG00000205426
COSMIC: KRT81

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000205426ENST00000327741Q14533
ENSG00000205426ENST00000615839A0A087X106

Expression (GTEx)

0
1
2
3

Pathways

PathwaySourceExternal ID
Developmental BiologyREACTOMER-HSA-1266738
KeratinizationREACTOMER-HSA-6805567

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
157974582005Keratins of the human hair follicle.39
217998792011A dual role for KRT81: a miR-SNP associated with recurrence in non-small-cell lung cancer and a novel marker of squamous cell lung carcinoma.26
225398022012Impact of MiRSNPs on survival and progression in patients with multiple myeloma undergoing autologous stem cell transplantation.26
291013032018Pancreatic Ductal Adenocarcinoma Subtyping Using the Biomarkers Hepatocyte Nuclear Factor-1A and Cytokeratin-81 Correlates with Outcome and Treatment Response.15
257164252015A genetic variation in microRNA target site of KRT81 gene is associated with survival in early-stage non-small-cell lung cancer.7
145206982003Upregulation of the truncated basic hair keratin 1(hHb1-DeltaN) in carcinoma cells by Epstein-Barr virus (EBV).6
245304792014A miR-SNP of the KRT81 gene is associated with the prognosis of non-Hodgkin's lymphoma.5
180212612008Transcriptional activation of a subset of hair keratin genes by the NF-kappaB effector p65/RelA.3
255572322015Novel KRT83 and KRT86 mutations associated with monilethrix.2
284056792017Hair keratin KRT81 is expressed in normal and breast cancer cells and contributes to their invasiveness.0

Citation

Dessen P

KRT81 (keratin 81)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45888/krt81