Identity
HGNC
LOCATION
14q22.3
LOCUSID
ALIAS
CG1,KNT,MU-RMS-40.19
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3895
MIM: 600381
HGNC: 6467
Ensembl: ENSG00000126777
Variants:
dbSNP: 3895
ClinVar: 3895
TCGA: ENSG00000126777
COSMIC: KTN1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Signal Transduction | REACTOME | R-HSA-162582 |
| Signaling by Rho GTPases | REACTOME | R-HSA-194315 |
| RHO GTPase Effectors | REACTOME | R-HSA-195258 |
| RHO GTPases activate KTN1 | REACTOME | R-HSA-5625970 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37992546 | 2024 | A genetic and transcriptomic assessment of the KTN1 gene in Parkinson's disease risk. | 0 |
| 38448340 | 2024 | KTN1 mediated unfolded protein response protects keratinocytes from ionizing radiation-induced DNA damage. | 0 |
| 37992546 | 2024 | A genetic and transcriptomic assessment of the KTN1 gene in Parkinson's disease risk. | 0 |
| 38448340 | 2024 | KTN1 mediated unfolded protein response protects keratinocytes from ionizing radiation-induced DNA damage. | 0 |
| 32115811 | 2021 | Significant, replicable, and functional associations between KTN1 variants and alcohol and drug codependence. | 5 |
| 34219129 | 2021 | Kinectin 1 promotes the growth of triple-negative breast cancer via directly co-activating NF-kappaB/p65 and enhancing its transcriptional activity. | 5 |
| 34591354 | 2021 | Human microRNA-182-5p and kinectin 1: Potential biomarkers for prognosis in oral squamous cell carcinoma. | 0 |
| 32115811 | 2021 | Significant, replicable, and functional associations between KTN1 variants and alcohol and drug codependence. | 5 |
| 34219129 | 2021 | Kinectin 1 promotes the growth of triple-negative breast cancer via directly co-activating NF-kappaB/p65 and enhancing its transcriptional activity. | 5 |
| 34591354 | 2021 | Human microRNA-182-5p and kinectin 1: Potential biomarkers for prognosis in oral squamous cell carcinoma. | 0 |
| 32190980 | 2020 | KTN1 variants and risk for attention deficit hyperactivity disorder. | 9 |
| 32525992 | 2020 | Rab18 regulates focal adhesion dynamics by interacting with kinectin-1 at the endoplasmic reticulum. | 9 |
| 32956741 | 2020 | Associations of attention distractibility with attention deficit and with variation in the KTN1 gene. | 2 |
| 32190980 | 2020 | KTN1 variants and risk for attention deficit hyperactivity disorder. | 9 |
| 32525992 | 2020 | Rab18 regulates focal adhesion dynamics by interacting with kinectin-1 at the endoplasmic reticulum. | 9 |
Citation
Dessen P
KTN1 (kinectin 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41108/ktn1
