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L2HGDH (L-2-hydroxyglutarate dehydrogenase)

Identity

Other namesC14orf160
HGNC (Hugo) L2HGDH
LocusID (NCBI) 79944
Location 14q21.3
Location_base_pair Starts at 50709152 and ends at 50778947 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)L2HGDH   20499
Entrez_Gene (NCBI)L2HGDH  79944  L-2-hydroxyglutarate dehydrogenase
Cards
GeneCards (Weizmann)L2HGDH
Ensembl (Hinxton)ENSG00000087299 [Gene_View]  chr14:50709152-50778947 [Contig_View]  L2HGDH [Vega]
AceView (NCBI)L2HGDH
Genatlas (Paris)L2HGDH
SOURCE (Stanford)NM_024884
Genomic and cartography
GoldenPath (UCSC)L2HGDH  -  14q21.3   chr14:50709152-50778947 -  14q21.3   [Description]    (hg19-Feb_2009)
EnsemblL2HGDH - 14q21.3 [CytoView]
Mapping of homologs : NCBIL2HGDH [Mapview]
OMIM236792   609584   
Gene and transcription
Genbank (Entrez)AK022680 AK292627 AK309294 AY757363 BC006117
RefSeq transcript (SRS)NM_024884
RefSeq transcript (Entrez)NM_024884
RefSeq genomic (SRS)AC_000146 NC_000014 NC_018925 NG_008092 NT_026437 NW_001838111 NW_004078079
RefSeq genomic (Entrez)AC_000146 NC_000014 NC_018925 NG_008092 NT_026437 NW_001838111 NW_004078079
Consensus coding sequences : CCDS (NCBI)L2HGDH
Cluster EST : UnigeneHs.256034 [ SRS ] Hs.256034 [ NCBI ]
CGAP (NCI)Hs.256034
Alternative Splicing : Fast-db (Paris)GSHG0009353
Alternative Splicing GalleryENSG00000087299
Gene ExpressionL2HGDH [ NCBI-GEO ]   L2HGDH [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H9P8 (SRS) Q9H9P8 (Uniprot)
NextProtQ9H9P8
With graphics : InterProQ9H9P8
Splice isoforms : SwissVarQ9H9P8(Swissvar)
Domains : Interpro (SRS)FAD-dep_OxRdtase   
Domains : Interpro (EBI)FAD-dep_OxRdtase   
Related proteins : CluSTrQ9H9P8
Domain families : Pfam (SRS)DAO (PF01266)   
Domain families : Pfam (Sanger)DAO (PF01266)   
Domain families : Pfam (NCBI)pfam01266   
DMDM79944
Blocks (Seattle)Q9H9P8
Human Protein AtlasENSG00000087299
HPRD12640
IPIIPI00016458   IPI00029239   IPI01025121   IPI01025001   IPI01025349   IPI01025212   
Protein Interaction databases
DIP (DOE-UCLA)Q9H9P8
IntAct (EBI)Q9H9P8
FunCoupENSG00000087299
REACTOMEL2HGDH
Protein Interaction Database79944
BioGRIDL2HGDH
InParanoidQ9H9P8
Interologous Interaction database Q9H9P8
IntegromeDBL2HGDH
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)L2HGDH
SNP (GeneSNP Utah)L2HGDH
SNP : HGBaseL2HGDH
Genetic variants : HAPMAPL2HGDH
Somatic Mutations in Cancer : COSMICL2HGDH 
CONAN: Copy Number AnalysisL2HGDH 
Mutations and Diseases : HGMDL2HGDH
OMIM236792    609584   
GENETests236792    609584   
Disease Genetic AssociationL2HGDH
Huge Navigator L2HGDH [HugePedia]  L2HGDH [HugeCancerGEM]
Genomic VariantsL2HGDH  L2HGDH [DGVbeta]
snp3D : Map Gene to Disease79944
General knowledge
Homologs : HomoloGeneL2HGDH
Homology/Alignments : Family Browser (UCSC)L2HGDH
Phylogenetic Trees/Animal Genes : TreeFamL2HGDH
Catalytic activity : Enzyme1.1.99.2 [ Enzyme-Expasy ]   1.1.99.2 [ Enzyme-SRS ]   1.1.99.2 [ IntEnz-EBI ]   1.1.99.2 [ BRENDA ]   1.1.99.2 [ KEGG ]   
Chemical/Protein Interactions : CTD79944
Chemical/Pharm GKB GenePA134971279
Clinical trialL2HGDH
Cancer Resource (Charite)ENSG00000087299
Ontology : AmiGOmitochondrion  mitochondrial inner membrane  2-oxoglutarate metabolic process  integral to membrane  integral to mitochondrial inner membrane  cellular protein metabolic process  small molecule metabolic process  2-hydroxyglutarate dehydrogenase activity  
Ontology : EGO-EBImitochondrion  mitochondrial inner membrane  2-oxoglutarate metabolic process  integral to membrane  integral to mitochondrial inner membrane  cellular protein metabolic process  small molecule metabolic process  2-hydroxyglutarate dehydrogenase activity  
Pathways : KEGGButanoate metabolism
Other databases
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
PubGeneL2HGDH
iHOPL2HGDH
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:40:33 CEST 2013
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