LAMP1 (lysosomal associated membrane protein 1)

2003-06-01  

Identity

HGNC
LOCATION
13q34
LOCUSID
ALIAS
CD107a,LAMPA,LGP120
FUSION GENES

Other Information

Locus ID:

NCBI: 3916
MIM: 153330
HGNC: 6499
Ensembl: ENSG00000185896

Variants:

dbSNP: 3916
ClinVar: 3916
TCGA: ENSG00000185896
COSMIC: LAMP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000185896ENST00000332556P11279
ENSG00000185896ENST00000332556A0A024RDY3

Expression (GTEx)

0
50
100
150
200
250
300
350
400
450
500

Pathways

PathwaySourceExternal ID
Autophagy - animalKEGGko04140
Autophagy - animalKEGGhsa04140
LysosomeKEGGko04142
LysosomeKEGGhsa04142
PhagosomeKEGGko04145
PhagosomeKEGGhsa04145
TuberculosisKEGGko05152
TuberculosisKEGGhsa05152
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
382157352024Comparative Analysis of Site-Specific N-glycosylation of LAMP1 from Breast Cancer Tissues.0
382189452024Loss of RND3/RHOE controls entosis through LAMP1 expression in hepatocellular carcinoma.2
382318762024Lysosomal membrane proteins LAMP1 and LIMP2 are segregated in the Golgi apparatus independently of their clathrin adaptor binding motif.0
382157352024Comparative Analysis of Site-Specific N-glycosylation of LAMP1 from Breast Cancer Tissues.0
382189452024Loss of RND3/RHOE controls entosis through LAMP1 expression in hepatocellular carcinoma.2
382318762024Lysosomal membrane proteins LAMP1 and LIMP2 are segregated in the Golgi apparatus independently of their clathrin adaptor binding motif.0
373908182023Lysosomal LAMP proteins regulate lysosomal pH by direct inhibition of the TMEM175 channel.13
373908182023Lysosomal LAMP proteins regulate lysosomal pH by direct inhibition of the TMEM175 channel.13
359696332022Human LAMP1 accelerates Lassa virus fusion and potently promotes fusion pore dilation upon forcing viral fusion with non-endosomal membrane.9
359696332022Human LAMP1 accelerates Lassa virus fusion and potently promotes fusion pore dilation upon forcing viral fusion with non-endosomal membrane.9
333726812021Mitochondria-lysosome membrane contacts are defective in GDAP1-related Charcot-Marie-Tooth disease.27
336406822021Porcine hemagglutinating encephalomyelitis virus induces atypical autophagy via opposite regulation of expression and nuclear translocation of transcription factor EB.3
333726812021Mitochondria-lysosome membrane contacts are defective in GDAP1-related Charcot-Marie-Tooth disease.27
336406822021Porcine hemagglutinating encephalomyelitis virus induces atypical autophagy via opposite regulation of expression and nuclear translocation of transcription factor EB.3
315449772020Deacetylation of LAMP1 drives lipophagy-dependent generation of free fatty acids by Abrus agglutinin to promote senescence in prostate cancer.16

Citation

Dessen P

LAMP1 (lysosomal associated membrane protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/41121/lamp1