Identity
HGNC
LOCATION
1q22
LOCUSID
ALIAS
ENDAP,HSPC003,MAPBPIP,MAPKSP1AP,ROBLD3,Ragulator2,p14
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 28956
MIM: 610389
HGNC: 29796
Ensembl: ENSG00000116586
Variants:
dbSNP: 28956
ClinVar: 28956
TCGA: ENSG00000116586
COSMIC: LAMTOR2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000116586 | ENST00000368302 | Q9Y2Q5 |
| ENSG00000116586 | ENST00000368304 | Q9Y2Q5 |
| ENSG00000116586 | ENST00000368305 | Q9Y2Q5 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37626304 | 2023 | VSIG2 promotes malignant progression of pancreatic ductal adenocarcinoma by enhancing LAMTOR2-mediated mTOR activation. | 2 |
| 37626304 | 2023 | VSIG2 promotes malignant progression of pancreatic ductal adenocarcinoma by enhancing LAMTOR2-mediated mTOR activation. | 2 |
| 29901254 | 2018 | Novel intra-genic large deletions of CTNNB1 gene identified in WT desmoid-type fibromatosis. | 7 |
| 29901254 | 2018 | Novel intra-genic large deletions of CTNNB1 gene identified in WT desmoid-type fibromatosis. | 7 |
| 23341997 | 2013 | Polymorphisms in the gene regions of the adaptor complex LAMTOR2/LAMTOR3 and their association with breast cancer risk. | 6 |
| 23341997 | 2013 | Polymorphisms in the gene regions of the adaptor complex LAMTOR2/LAMTOR3 and their association with breast cancer risk. | 6 |
| 22968171 | 2012 | A complex immunodeficiency is based on U1 snRNP-mediated poly(A) site suppression. | 17 |
| 22968171 | 2012 | A complex immunodeficiency is based on U1 snRNP-mediated poly(A) site suppression. | 17 |
| 21829671 | 2011 | Simulating EGFR-ERK signaling control by scaffold proteins KSR and MP1 reveals differential ligand-sensitivity co-regulated by Cbl-CIN85 and endophilin. | 6 |
| 21829671 | 2011 | Simulating EGFR-ERK signaling control by scaffold proteins KSR and MP1 reveals differential ligand-sensitivity co-regulated by Cbl-CIN85 and endophilin. | 6 |
| 20381137 | 2010 | Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids. | 1268 |
| 20381137 | 2010 | Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids. | 1268 |
Citation
Dessen P
LAMTOR2 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-12-01
Online version: http://atlasgeneticsoncology.org/gene/49903/lamtor2
