Identity
HGNC
LOCATION
4q23
LOCUSID
ALIAS
MAP2K1IP1,MAPBP,MAPKSP1,MP1,PRO0633,Ragulator3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8649
MIM: 603296
HGNC: 15606
Ensembl: ENSG00000109270
Variants:
dbSNP: 8649
ClinVar: 8649
TCGA: ENSG00000109270
COSMIC: LAMTOR3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000109270 | ENST00000226522 | Q9UHA4 |
| ENSG00000109270 | ENST00000499666 | Q9UHA4 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36082464 | 2022 | LAMTOR3 is a prognostic biomarker in kidney renal clear cell carcinoma. | 3 |
| 36082464 | 2022 | LAMTOR3 is a prognostic biomarker in kidney renal clear cell carcinoma. | 3 |
| 33184989 | 2020 | Circ_0075829 facilitates the progression of pancreatic carcinoma by sponging miR-1287-5p and activating LAMTOR3 signalling. | 14 |
| 33184989 | 2020 | Circ_0075829 facilitates the progression of pancreatic carcinoma by sponging miR-1287-5p and activating LAMTOR3 signalling. | 14 |
| 31699189 | 2019 | [Expression and Clinical Significance of Late Endosomal/Lysosomal Adaptor,Mitogen-activated Protein Kinase and Mammalian Target of Rapamycin Activator 3 in Bladder Carcinoma]. | 0 |
| 31699189 | 2019 | [Expression and Clinical Significance of Late Endosomal/Lysosomal Adaptor,Mitogen-activated Protein Kinase and Mammalian Target of Rapamycin Activator 3 in Bladder Carcinoma]. | 0 |
| 28606806 | 2017 | BCL2 induced by LAMTOR3/MAPK is a druggable target of chemoradioresistance in mesenchymal lung cancer. | 18 |
| 28830458 | 2017 | Role of MEK partner-1 in cancer stemness through MEK/ERK pathway in cancerous neural stem cells, expressing EGFRviii. | 11 |
| 28606806 | 2017 | BCL2 induced by LAMTOR3/MAPK is a druggable target of chemoradioresistance in mesenchymal lung cancer. | 18 |
| 28830458 | 2017 | Role of MEK partner-1 in cancer stemness through MEK/ERK pathway in cancerous neural stem cells, expressing EGFRviii. | 11 |
| 25661340 | 2015 | A miR-29c binding site genetic variant in the 3'-untranslated region of LAMTOR3 gene is associated with gastric cancer risk. | 3 |
| 25661340 | 2015 | A miR-29c binding site genetic variant in the 3'-untranslated region of LAMTOR3 gene is associated with gastric cancer risk. | 3 |
| 23341997 | 2013 | Polymorphisms in the gene regions of the adaptor complex LAMTOR2/LAMTOR3 and their association with breast cancer risk. | 6 |
| 23408059 | 2013 | Gastrin-induced proliferation involves MEK partner 1 (MP1). | 9 |
| 23341997 | 2013 | Polymorphisms in the gene regions of the adaptor complex LAMTOR2/LAMTOR3 and their association with breast cancer risk. | 6 |
Citation
Dessen P
LAMTOR3 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 3)
Atlas Genet Cytogenet Oncol Haematol. 2011-03-01
Online version: http://atlasgeneticsoncology.org/gene/52098/lamtor3
