Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3937
MIM: 601603
HGNC: 6529
Ensembl: ENSG00000043462
Variants:
dbSNP: 3937
ClinVar: 3937
TCGA: ENSG00000043462
COSMIC: LCP2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000043462 | ENST00000046794 | Q13094 |
| ENSG00000043462 | ENST00000520344 | E5RKA2 |
| ENSG00000043462 | ENST00000521416 | E7ESF6 |
| ENSG00000043462 | ENST00000628092 | A0A0D9SGG1 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37477758 | 2024 | WTAP Mediates NUPR1 Regulation of LCN2 Through m(6)A Modification to Influence Ferroptosis, Thereby Promoting Breast Cancer Proliferation, Migration and Invasion. | 2 |
| 37477758 | 2024 | WTAP Mediates NUPR1 Regulation of LCN2 Through m(6)A Modification to Influence Ferroptosis, Thereby Promoting Breast Cancer Proliferation, Migration and Invasion. | 2 |
| 36474126 | 2023 | SLP76 Mutation Associated with Combined Immunodeficiency and EBV-Related Lymphoma. | 1 |
| 36474126 | 2023 | SLP76 Mutation Associated with Combined Immunodeficiency and EBV-Related Lymphoma. | 1 |
| 33159816 | 2021 | The 14-3-3/SLP76 protein-protein interaction in T-cell receptor signalling: a structural and biophysical characterization. | 4 |
| 33436632 | 2021 | Targeting adaptor protein SLP76 of RAGE as a therapeutic approach for lethal sepsis. | 18 |
| 33911146 | 2021 | A novel prognostic biomarker LCP2 correlates with metastatic melanoma-infiltrating CD8(+) T cells. | 13 |
| 34112215 | 2021 | STAT1 epigenetically regulates LCP2 and TNFAIP2 by recruiting EP300 to contribute to the pathogenesis of inflammatory bowel disease. | 12 |
| 34816740 | 2021 | Lymphocyte cytosolic protein 2 is a novel prognostic marker in lung adenocarcinoma. | 7 |
| 33159816 | 2021 | The 14-3-3/SLP76 protein-protein interaction in T-cell receptor signalling: a structural and biophysical characterization. | 4 |
| 33436632 | 2021 | Targeting adaptor protein SLP76 of RAGE as a therapeutic approach for lethal sepsis. | 18 |
| 33911146 | 2021 | A novel prognostic biomarker LCP2 correlates with metastatic melanoma-infiltrating CD8(+) T cells. | 13 |
| 34112215 | 2021 | STAT1 epigenetically regulates LCP2 and TNFAIP2 by recruiting EP300 to contribute to the pathogenesis of inflammatory bowel disease. | 12 |
| 34816740 | 2021 | Lymphocyte cytosolic protein 2 is a novel prognostic marker in lung adenocarcinoma. | 7 |
| 30305305 | 2018 | ADAP is an upstream regulator that precedes SLP-76 at sites of TCR engagement and stabilizes signaling microclusters. | 12 |
Citation
Dessen P
LCP2 (lymphocyte cytosolic protein 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45540/lcp2
