LEAP2 (liver enriched antimicrobial peptide 2)

2010-03-01  

Identity

HGNC
LOCATION
5q31.1
LOCUSID
ALIAS
LEAP-2
FUSION GENES

Other Information

Locus ID:

NCBI: 116842
MIM: 611373
HGNC: 29571
Ensembl: ENSG00000164406

Variants:

dbSNP: 116842
ClinVar: 116842
TCGA: ENSG00000164406
COSMIC: LEAP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164406ENST00000296877Q969E1

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Antimicrobial peptidesREACTOMER-HSA-6803157

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
208453582010Structural and functional analysis of human liver-expressed antimicrobial peptide 2.8
208453582010Structural and functional analysis of human liver-expressed antimicrobial peptide 2.8
314244242019LEAP2 changes with body mass and food intake in humans and mice.7
198529902010Structure-activity relationship of human liver-expressed antimicrobial peptide 2.6
200384632010Expression and functional analyses of liver expressed antimicrobial peptide-2 (LEAP-2) variant forms in human tissues.6
273353442016Overexpression of Leap2 impairs Xenopus embryonic development and modulates FGF and activin signals.0
317701062020Plasma levels of ghrelin, des-acyl ghrelin and LEAP2 in children with obesity: correlation with age and insulin resistance.0

Citation

Dessen P

LEAP2 (liver enriched antimicrobial peptide 2)

Atlas Genet Cytogenet Oncol Haematol. 2010-03-01

Online version: http://atlasgeneticsoncology.org/gene/51383/leap2