Identity
HGNC
LOCATION
4q25
LOCUSID
ALIAS
LEF-1,TCF10,TCF1ALPHA,TCF7L3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51176
MIM: 153245
HGNC: 6551
Ensembl: ENSG00000138795
Variants:
dbSNP: 51176
ClinVar: 51176
TCGA: ENSG00000138795
COSMIC: LEF1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38169425 | 2024 | Downregulation of TCF7 and LEF1 is a key determinant of tumor-infiltrating regulatory T-cell function. | 0 |
| 38169425 | 2024 | Downregulation of TCF7 and LEF1 is a key determinant of tumor-infiltrating regulatory T-cell function. | 0 |
| 36484736 | 2023 | LEF1 Drives a Central Memory Program and Supports Antitumor Activity of Natural Killer T Cells. | 5 |
| 36647795 | 2023 | Onychomatricoma: a clinicopathological, immunohistochemical, and molecular study of 10 cases highlighting recurrent RB1 deletion and the potential diagnostic value of LEF-1. | 1 |
| 36877308 | 2023 | Altered levels of lymphocyte enhancer-binding factor-1 modulates the pigmentation in acral and non-acral lesions of non-segmental vitiligo patients: a follow-up-based study in North India. | 1 |
| 36997001 | 2023 | Proteogenomic Profiling of High-Grade B-Cell Lymphoma With 11q Aberrations and Burkitt Lymphoma Reveals Lymphoid Enhancer Binding Factor 1 as a Novel Biomarker. | 0 |
| 37106379 | 2023 | The β-catenin-LINC00183-miR-371b-5p-Smad2/LEF1 axis promotes adult T-cell lymphoblastic lymphoma progression and chemoresistance. | 7 |
| 37462205 | 2023 | PRAME and LEF1 in Combined Deep Penetrating Nevus and Combined Blue Nevus: Utility and Pitfalls. | 0 |
| 37523793 | 2023 | PD1 is transcriptionally regulated by LEF1 in mature T cells. | 1 |
| 37530485 | 2023 | Constant small-cell changes and variable LEF1 expression in DUSP22-rearranged primary cutaneous anaplastic large-cell lymphoma: Analysis of the repeated biopsies of three patients. | 0 |
| 37553362 | 2023 | Carcinogenesis promotion in oral squamous cell carcinoma: KDM4A complex-mediated gene transcriptional suppression by LEF1. | 1 |
| 37961030 | 2023 | LEF1 isoforms regulate cellular senescence and aging. | 2 |
| 38113273 | 2023 | A distinct isoform of lymphoid enhancer binding factor 1 (LEF1) epigenetically restricts EBV reactivation to maintain viral latency. | 1 |
| 36484736 | 2023 | LEF1 Drives a Central Memory Program and Supports Antitumor Activity of Natural Killer T Cells. | 5 |
| 36647795 | 2023 | Onychomatricoma: a clinicopathological, immunohistochemical, and molecular study of 10 cases highlighting recurrent RB1 deletion and the potential diagnostic value of LEF-1. | 1 |
Citation
Dessen P
LEF1 (lymphoid enhancer binding factor 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/401/lef1
