LEKR1 (leucine, glutamate and lysine rich 1)

2014-11-01 Affiliation

Identity

HGNC

LEKR1

LOCATION

3q25.31

LOCUSID

389170

ALIAS

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 389170
MIM: 613536
HGNC: 33765
Ensembl: ENSG00000197980

Variants:

dbSNP: 389170
ClinVar: 389170
TCGA: ENSG00000197980
COSMIC: LEKR1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000197980	ENST00000356539	J3KP02
ENSG00000197980	ENST00000470811	Q6ZMV7
ENSG00000197980	ENST00000477399	D3DNK7
ENSG00000197980	ENST00000483177	D6RAK6
ENSG00000197980	ENST00000491763	D3DNK7
ENSG00000197980	ENST00000498839	D6RJ01
ENSG00000197980	ENST00000640869	A0A1W2PPA8

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
25898001	2015	Genetic variants in LEKR1 and GALNT10 modulate sex-difference in carotid intima-media thickness: a genome-wide interaction study.	11
22073261	2011	The birth weight lowering C-allele of rs900400 near LEKR1 and CCNL1 associates with elevated insulin release following an oral glucose challenge.	7
27607899	2016	Association between LEKR1-CCNL1 and IGSF21-KLHDC7A gene polymorphisms and diabetic retinopathy of type 2 diabetes mellitus in the Chinese Han population.	2

Citation

Dessen P

LEKR1 (leucine, glutamate and lysine rich 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/65225/lekr1