LILRA6 (leukocyte immunoglobulin like receptor A6)

2014-11-01 Affiliation

Identity

HGNC

LILRA6

LOCATION

19q13.42

LOCUSID

79168

ALIAS

CD85b,ILT-8,ILT5,ILT8,LILRB3,LILRB6

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 79168
HGNC: 15495
Ensembl: ENSG00000244482

Variants:

dbSNP: 79168
ClinVar: 79168
TCGA: ENSG00000244482
COSMIC: LILRA6

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000244482	ENST00000245621	B5ME96
ENSG00000244482	ENST00000396365	Q6PI73
ENSG00000244482	ENST00000396365	U5XH19
ENSG00000244482	ENST00000430421	Q6PI73

Expression (GTEx)

100

150

200

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Osteoclast differentiation	KEGG	ko04380
Osteoclast differentiation	KEGG	hsa04380
Immune System	REACTOME	R-HSA-168256
Adaptive Immune System	REACTOME	R-HSA-1280218
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	REACTOME	R-HSA-198933

References

Pubmed ID	Year	Title	Citations
20331378	2010	Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus.	29
19617579	2009	Allogeneic disparities in immunoglobulin-like transcript 5 induce potent antibody responses in hematopoietic stem cell transplant recipients.	12
24096970	2014	Diversity of the human LILRB3/A6 locus encoding a myeloid inhibitory and activating receptor pair.	8
27333811	2016	LILRA6 copy number variation correlates with susceptibility to atopic dermatitis.	3

Citation

Dessen P

LILRA6 (leukocyte immunoglobulin like receptor A6)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/65264/lilra6