Identity
HGNC
LOCATION
19q13.42
LOCUSID
ALIAS
CD85K,ILT-3,ILT3,LIR-5,LIR5
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 11006
MIM: 604821
HGNC: 6608
Ensembl: ENSG00000186818
Variants:
dbSNP: 11006
ClinVar: 11006
TCGA: ENSG00000186818
COSMIC: LILRB4
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38324114 | 2024 | Downregulation of LILRB4 Promotes Human Aortic Smooth Muscle Cell Contractile Phenotypic Switch and Apoptosis in Aortic Dissection. | 1 |
| 38397424 | 2024 | LILRB4 Checkpoint for Immunotherapy: Structure, Mechanism and Disease Targets. | 1 |
| 38951916 | 2024 | LILRB4 on multiple myeloma cells promotes bone lesion by p-SHP2/NF-κB/RELT signal pathway. | 0 |
| 38324114 | 2024 | Downregulation of LILRB4 Promotes Human Aortic Smooth Muscle Cell Contractile Phenotypic Switch and Apoptosis in Aortic Dissection. | 1 |
| 38397424 | 2024 | LILRB4 Checkpoint for Immunotherapy: Structure, Mechanism and Disease Targets. | 1 |
| 38951916 | 2024 | LILRB4 on multiple myeloma cells promotes bone lesion by p-SHP2/NF-κB/RELT signal pathway. | 0 |
| 37461040 | 2023 | LILRB4 regulates the function of decidual MDSCs via the SHP-2/STAT6 pathway during Toxoplasma gondii infection. | 6 |
| 37461040 | 2023 | LILRB4 regulates the function of decidual MDSCs via the SHP-2/STAT6 pathway during Toxoplasma gondii infection. | 6 |
| 32918786 | 2021 | Leukocyte immunoglobulin-like receptor B1 and B4 (LILRB1 and LILRB4): Highly sensitive and specific markers of acute myeloid leukemia with monocytic differentiation. | 8 |
| 33152402 | 2021 | ILT3 promotes tumor cell motility and angiogenesis in non-small cell lung cancer. | 21 |
| 33372059 | 2021 | ILT3 (LILRB4) Promotes the Immunosuppressive Function of Tumor-Educated Human Monocytic Myeloid-Derived Suppressor Cells. | 27 |
| 33974041 | 2021 | LILRB4 suppresses immunity in solid tumors and is a potential target for immunotherapy. | 39 |
| 34089617 | 2021 | Blockade of checkpoint ILT3/LILRB4/gp49B binding to fibronectin ameliorates autoimmune disease in BXSB/Yaa mice. | 8 |
| 34425800 | 2021 | Upregulation of leukocyte immunoglobulin-like receptor B4 on interstitial macrophages in COPD; their possible protective role against emphysema formation. | 5 |
| 32918786 | 2021 | Leukocyte immunoglobulin-like receptor B1 and B4 (LILRB1 and LILRB4): Highly sensitive and specific markers of acute myeloid leukemia with monocytic differentiation. | 8 |
Citation
Dessen P
LILRB4 (leukocyte immunoglobulin like receptor B4)
Atlas Genet Cytogenet Oncol Haematol. 2007-07-01
Online version: http://atlasgeneticsoncology.org/gene/47591/lilrb4
