Identity
HGNC
LOCATION
2q12.3
LOCUSID
ALIAS
PINCH,PINCH-1,PINCH1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3987
MIM: 602567
HGNC: 6616
Ensembl: ENSG00000169756
Variants:
dbSNP: 3987
ClinVar: 3987
TCGA: ENSG00000169756
COSMIC: LIMS1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38618967 | 2024 | The RNA-binding protein RBMS3 inhibits the progression of colon cancer by regulating the stability of LIMS1 mRNA. | 1 |
| 38618967 | 2024 | The RNA-binding protein RBMS3 inhibits the progression of colon cancer by regulating the stability of LIMS1 mRNA. | 1 |
| 33529444 | 2021 | A mechanoresponsive PINCH-1-Notch2 interaction regulates smooth muscle differentiation of human placental mesenchymal stem cells. | 5 |
| 33587032 | 2021 | Complex structures of Rsu1 and PINCH1 reveal a regulatory mechanism of the ILK/PINCH/Parvin complex for F-actin dynamics. | 5 |
| 33891945 | 2021 | Molecular basis for Ras suppressor-1 binding to PINCH-1 in focal adhesion assembly. | 2 |
| 33529444 | 2021 | A mechanoresponsive PINCH-1-Notch2 interaction regulates smooth muscle differentiation of human placental mesenchymal stem cells. | 5 |
| 33587032 | 2021 | Complex structures of Rsu1 and PINCH1 reveal a regulatory mechanism of the ILK/PINCH/Parvin complex for F-actin dynamics. | 5 |
| 33891945 | 2021 | Molecular basis for Ras suppressor-1 binding to PINCH-1 in focal adhesion assembly. | 2 |
| 31801973 | 2020 | PINCH-1 interacts with myoferlin to promote breast cancer progression and metastasis. | 9 |
| 32746944 | 2020 | Inflammation-induced PINCH expression leads to actin depolymerization and mitochondrial mislocalization in neurons. | 4 |
| 32751711 | 2020 | MicroRNA-Dependent Targeting of RSU1 and the IPP Adhesion Complex Regulates the PTEN/PI3K/AKT Signaling Pathway in Breast Cancer Cell Lines. | 2 |
| 33004813 | 2020 | PINCH-1 regulates mitochondrial dynamics to promote proline synthesis and tumor growth. | 25 |
| 31801973 | 2020 | PINCH-1 interacts with myoferlin to promote breast cancer progression and metastasis. | 9 |
| 32746944 | 2020 | Inflammation-induced PINCH expression leads to actin depolymerization and mitochondrial mislocalization in neurons. | 4 |
| 32751711 | 2020 | MicroRNA-Dependent Targeting of RSU1 and the IPP Adhesion Complex Regulates the PTEN/PI3K/AKT Signaling Pathway in Breast Cancer Cell Lines. | 2 |
Citation
Dessen P
LIMS1 (LIM zinc finger domain containing 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45926/lims1
