LINP1 (lncRNA in non-homologous end joining pathway 1)

2017-08-01 Affiliation

Identity

HGNC

LINP1

LOCATION

10p14

LOCUSID

108570035

ALIAS

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 108570035
HGNC: 53170

Variants:

dbSNP: 108570035
ClinVar: 108570035
COSMIC: LINP1

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title
27111890	2016	Long noncoding RNA LINP1 regulates repair of DNA double-strand breaks in triple-negative breast cancer.
29293402	2018	Long noncoding RNA LINP1 acts as an oncogene and promotes chemoresistance in breast cancer.
29527968	2018	LINP1 facilitates DNA damage repair through non-homologous end joining (NHEJ) pathway and subsequently decreases the sensitivity of cervical cancer cells to ionizing radiation.
30058678	2018	Long non-coding RNA LINP1 promotes the malignant progression of prostate cancer by regulating p53.
30575915	2018	Increased long noncoding RNA LINP1 expression and its prognostic significance in human breast cancer.
31325181	2019	LncRNA LINP1 regulates acute myeloid leukemia progression via HNF4α/AMPK/WNT5A signaling pathway.

Citation

Dessen P

LINP1 (lncRNA in non-homologous end joining pathway 1)

Atlas Genet Cytogenet Oncol Haematol. 2017-08-01

Online version: http://atlasgeneticsoncology.org/gene/56971/linp1