LMAN1L (lectin, mannose binding 1 like)

2003-05-01 Affiliation

Identity

HGNC

LMAN1L

LOCATION

15q24.1

LOCUSID

79748

ALIAS

ERGIC-53L,ERGL

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 79748
MIM: 609548
HGNC: 6632
Ensembl: ENSG00000140506

Variants:

dbSNP: 79748
ClinVar: 79748
TCGA: ENSG00000140506
COSMIC: LMAN1L

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000140506	ENST00000309664	Q9HAT1
ENSG00000140506	ENST00000379709	Q9HAT1
ENSG00000140506	ENST00000562810	H3BSC9
ENSG00000140506	ENST00000567848	H3BN74

Expression (GTEx)

100

150

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Protein processing in endoplasmic reticulum	KEGG	ko04141
Protein processing in endoplasmic reticulum	KEGG	hsa04141
Metabolism of proteins	REACTOME	R-HSA-392499
Post-translational protein modification	REACTOME	R-HSA-597592
Asparagine N-linked glycosylation	REACTOME	R-HSA-446203
Transport to the Golgi and subsequent modification	REACTOME	R-HSA-948021
ER to Golgi Anterograde Transport	REACTOME	R-HSA-199977
COPII (Coat Protein 2) Mediated Vesicle Transport	REACTOME	R-HSA-204005
Vesicle-mediated transport	REACTOME	R-HSA-5653656
Membrane Trafficking	REACTOME	R-HSA-199991
Cargo concentration in the ER	REACTOME	R-HSA-5694530

References

Pubmed ID	Year	Title	Citations
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	62
18283111	2008	Identification of ERGIC-53 as an intracellular transport receptor of alpha1-antitrypsin.	47
17805346	2007	Sequential steps and checkpoints in the early exocytic compartment during secretory IgM biogenesis.	46
20237496	2010	New genetic associations detected in a host response study to hepatitis B vaccine.	27
18056485	2008	The sugar-binding ability of ERGIC-53 is enhanced by its interaction with MCFD2.	17

Citation

Dessen P

LMAN1L (lectin, mannose binding 1 like)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/41164/lman1l