LNX2 (ligand of numb-protein X 2)

2007-04-01  

Identity

HGNC
LOCATION
13q12.2
LOCUSID
ALIAS
PDZRN1
FUSION GENES

Other Information

Locus ID:

NCBI: 222484
MIM: 609733
HGNC: 20421
Ensembl: ENSG00000139517

Variants:

dbSNP: 222484
ClinVar: 222484
TCGA: ENSG00000139517
COSMIC: LNX2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000139517ENST00000316334Q8N448
ENSG00000139517ENST00000649248Q8N448

Expression (GTEx)

0
5
10
15
20

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
233198042013Genetic amplification of the NOTCH modulator LNX2 upregulates the WNT/β-catenin pathway in colorectal cancer.26
220457312011Ligand of Numb proteins LNX1p80 and LNX2 interact with the human glycoprotein CD8α and promote its ubiquitylation and endocytosis.11
220669092012The ligands of Numb proteins X1 and X2 are specific markers for chronic Q fever.1

Citation

Dessen P

LNX2 (ligand of numb-protein X 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47042/lnx2