LORICRIN (loricrin cornified envelope precursor protein)

2016-10-01 Affiliation

HGNC

LORICRIN

LOCATION

1q21.3

LOCUSID

4014

ALIAS

LOR

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

dbSNP: 4014
ClinVar: 4014
TCGA: ENSG00000203782
COSMIC: LORICRIN

Gene ID	Transcript ID	Uniprot
ENSG00000203782	ENST00000368742	P23490

Pathway	Source	External ID
Developmental Biology	REACTOME	R-HSA-1266738
Keratinization	REACTOME	R-HSA-6805567
Formation of the cornified envelope	REACTOME	R-HSA-6809371

Pubmed ID	Year	Title	Citations
18166499	2008	Loricrin and involucrin expression is down-regulated by Th2 cytokines through STAT-6.	92
12200429	2002	Loricrin expression in cultured human keratinocytes is controlled by a complex interplay between transcription factors of the Sp1, CREB, AP1, and AP2 families.	24
15102081	2004	Structural and functional consequences of loricrin mutations in human loricrin keratoderma (Vohwinkel syndrome with ichthyosis).	21
20634891	2010	Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.	18
25896246	2015	Barrier Function of the Repaired Skin Is Disrupted Following Arrest of Dicer in Keratinocytes.	18
12615358	2003	Loricrin keratoderma: a novel disease entity characterized by nuclear accumulation of mutant loricrin.	12
20184865	2010	Protein kinase C delta and eta differently regulate the expression of loricrin and Jun family proteins in human keratinocytes.	10
19672094	2010	Locus 1q21 Gene expression changes in atopic dermatitis skin lesions: deregulation of small proline-rich region 1A.	7
21221983	2011	mRNA-based skin identification for forensic applications.	5
15598222	2004	Characterization of the loricrin (LOR) gene as a positional candidate for the PSORS4 psoriasis susceptibility locus.	4

Dessen P

LORICRIN (loricrin cornified envelope precursor protein)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01