Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4018
MIM: 152200
HGNC: 6667
Ensembl: ENSG00000198670
Variants:
dbSNP: 4018
ClinVar: 4018
TCGA: ENSG00000198670
COSMIC: LPA
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000198670 | ENST00000316300 | P08519 |
| ENSG00000198670 | ENST00000447678 | P08519 |
| ENSG00000198670 | ENST00000614786 | A0A087WWY0 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA133950441 | hmg coa reductase inhibitors | Chemical | ClinicalAnnotation | associated | PD | 22331829, 23903772, 25350695, 27045730, 29703846 | |
| PA443796 | Coronary Artery Disease | Disease | ClinicalAnnotation | associated | PD | 22331829, 23903772, 25350695, 27045730, 29703846 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37392838 | 2024 | Dysregulation of the LPC-ATX-LPA axis in autoimmune hepatitis is associated with monocyte activation. | 1 |
| 37553064 | 2024 | Association Between Lipoprotein (a) and Risk of Atrial Fibrillation: A Systematic Review and Meta-analysis of Mendelian Randomization Studies. | 5 |
| 37650693 | 2024 | Lipoprotein(a) and calcific aortic valve disease: current evidence and future directions. | 0 |
| 37777699 | 2024 | Lipoprotein(a) is associated with recurrent cardiovascular events in patients with coronary artery disease and prediabetes or diabetes. | 4 |
| 37937463 | 2024 | Major Facilitator Superfamily Domain Containing 5 Inhibition Reduces Lipoprotein(a) Uptake and Calcification in Valvular Heart Disease. | 1 |
| 37938756 | 2024 | Lipoprotein(a), platelet function and cardiovascular disease. | 3 |
| 37997792 | 2024 | The 10 essential questions regarding lipoprotein(a). | 0 |
| 38065715 | 2024 | Lipoprotein(a) levels and carotid intima-media thickness in children: A 20-year follow-up study. | 1 |
| 38101270 | 2024 | The association of lipoprotein (a) with coronary artery calcification: A systematic review and meta-analysis. | 0 |
| 38239089 | 2024 | Association of Lipoprotein(a) with arterial stiffness: A Mendelian randomization study. | 0 |
| 38254171 | 2024 | Predictive value of lipoprotein(a) for left atrial thrombus or spontaneous echo contrast in non-valvular atrial fibrillation patients with low CHA(2)DS(2)-VASc scores: a cross-sectional study. | 1 |
| 38255810 | 2024 | Haplotype of the Lipoprotein(a) Gene Variants rs10455872 and rs3798220 Is Associated with Parameters of Coagulation, Fibrinolysis, and Inflammation in Patients after Myocardial Infarction and Highly Elevated Lipoprotein(a) Values. | 0 |
| 38269588 | 2024 | Diacylglycerols and Lysophosphatidic Acid, Enriched on Lipoprotein(a), Contribute to Monocyte Inflammation. | 1 |
| 38301917 | 2024 | Association between lipoprotein (a) and risk of heart failure: A systematic review and meta-analysis of Mendelian randomization studies. | 0 |
| 38722118 | 2024 | Confounding Factors Responsible for Elevated Lp(a) Levels in Patients with Coronary Artery Disease. | 0 |
Citation
Dessen P
LPA (lipoprotein(a))
Atlas Genet Cytogenet Oncol Haematol. 2008-05-01
Online version: http://atlasgeneticsoncology.org/gene/50112/lpa
