Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9227
MIM: 604863
HGNC: 6685
Ensembl: ENSG00000121207
Variants:
dbSNP: 9227
ClinVar: 9227
TCGA: ENSG00000121207
COSMIC: LRAT
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000121207 | ENST00000336356 | O95237 |
| ENSG00000121207 | ENST00000502525 | D6RC94 |
| ENSG00000121207 | ENST00000507827 | O95237 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 29973277 | 2018 | A novel LRAT mutation affecting splicing in a family with early onset retinitis pigmentosa. | 7 |
| 29973277 | 2018 | A novel LRAT mutation affecting splicing in a family with early onset retinitis pigmentosa. | 7 |
| 28758396 | 2017 | Impact of LCA-Associated E14L LRAT Mutation on Protein Stability and Retinoid Homeostasis. | 7 |
| 28942093 | 2017 | A novel homozygous mutation causing lecithin-cholesterol acyltransferase deficiency in a proband of Romanian origin with a record of extreme gestational hyperlipidemia. | 4 |
| 28758396 | 2017 | Impact of LCA-Associated E14L LRAT Mutation on Protein Stability and Retinoid Homeostasis. | 7 |
| 28942093 | 2017 | A novel homozygous mutation causing lecithin-cholesterol acyltransferase deficiency in a proband of Romanian origin with a record of extreme gestational hyperlipidemia. | 4 |
| 25383759 | 2015 | LRAT-specific domain facilitates vitamin A metabolism by domain swapping in HRASLS3. | 32 |
| 25383759 | 2015 | LRAT-specific domain facilitates vitamin A metabolism by domain swapping in HRASLS3. | 32 |
| 23890161 | 2014 | Hepatic stellate cells that coexpress LRAT and CRBP-1 partially contribute to portal fibrogenesis in patients with human viral hepatitis. | 5 |
| 24613493 | 2014 | Enzymatic activity of Lecithin:retinol acyltransferase: a thermostable and highly active enzyme with a likely mode of interfacial activation. | 2 |
| 25236354 | 2014 | Knockdown of lecithin retinol acyltransferase increases all-trans retinoic acid levels and restores retinoid sensitivity in malignant melanoma cells. | 2 |
| 25260806 | 2014 | High incidence of LRAT promoter hypermethylation in colorectal cancer correlates with tumor stage. | 6 |
| 23890161 | 2014 | Hepatic stellate cells that coexpress LRAT and CRBP-1 partially contribute to portal fibrogenesis in patients with human viral hepatitis. | 5 |
| 24613493 | 2014 | Enzymatic activity of Lecithin:retinol acyltransferase: a thermostable and highly active enzyme with a likely mode of interfacial activation. | 2 |
| 25236354 | 2014 | Knockdown of lecithin retinol acyltransferase increases all-trans retinoic acid levels and restores retinoid sensitivity in malignant melanoma cells. | 2 |
Citation
Dessen P
LRAT (lecithin retinol acyltransferase)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43955/lrat
