Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4040
MIM: 603507
HGNC: 6698
Ensembl: ENSG00000070018
Variants:
dbSNP: 4040
ClinVar: 4040
TCGA: ENSG00000070018
COSMIC: LRP6
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38250152 | 2024 | The inhibition of YTHDF3/m(6)A/LRP6 reprograms fatty acid metabolism and suppresses lymph node metastasis in cervical cancer. | 1 |
| 38250152 | 2024 | The inhibition of YTHDF3/m(6)A/LRP6 reprograms fatty acid metabolism and suppresses lymph node metastasis in cervical cancer. | 1 |
| 36638182 | 2023 | A genetic variant of the Wnt receptor LRP6 accelerates synapse degeneration during aging and in Alzheimer's disease. | 7 |
| 36694134 | 2023 | LRP6/filamentous-actin signaling facilitates osteogenic commitment in mechanically induced periodontal ligament stem cells. | 4 |
| 36925229 | 2023 | Overexpression of circRNAs LRP6 in gestational diabetes mellitus predicts foetal malformation and intrauterine death. | 0 |
| 37202775 | 2023 | LRP5-/6 gene polymorphisms and its association with risk of abnormal bone mass in postmenopausal women. | 0 |
| 36638182 | 2023 | A genetic variant of the Wnt receptor LRP6 accelerates synapse degeneration during aging and in Alzheimer's disease. | 7 |
| 36694134 | 2023 | LRP6/filamentous-actin signaling facilitates osteogenic commitment in mechanically induced periodontal ligament stem cells. | 4 |
| 36925229 | 2023 | Overexpression of circRNAs LRP6 in gestational diabetes mellitus predicts foetal malformation and intrauterine death. | 0 |
| 37202775 | 2023 | LRP5-/6 gene polymorphisms and its association with risk of abnormal bone mass in postmenopausal women. | 0 |
| 34896607 | 2022 | Variants in the Wnt co-receptor LRP6 are associated with familial exudative vitreoretinopathy. | 12 |
| 35211755 | 2022 | circ‑LRP6 contributes to osteosarcoma progression by regulating the miR‑141‑3p/HDAC4/HMGB1 axis. | 6 |
| 35277657 | 2022 | SIK2 maintains breast cancer stemness by phosphorylating LRP6 and activating Wnt/β-catenin signaling. | 9 |
| 35840698 | 2022 | An LRP6 mutation (Arg360His) associated with low bone mineral density but not cardiovascular events in a Caucasian family. | 2 |
| 35961235 | 2022 | Mutations in LRP6 highlight the role of WNT signaling in oral exostoses and dental anomalies. | 8 |
Citation
Dessen P
LRP6 (LDL receptor related protein 6)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/461/lrp6
