Identity
HGNC
LOCATION
4p16.3
LOCUSID
ALIAS
A2MRAP,A2RAP,HBP44,MRAP,MYP23,RAP,alpha-2-MRAP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4043
MIM: 104225
HGNC: 6701
Ensembl: ENSG00000163956
Variants:
dbSNP: 4043
ClinVar: 4043
TCGA: ENSG00000163956
COSMIC: LRPAP1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000163956 | ENST00000515119 | D6REW6 |
| ENSG00000163956 | ENST00000648517 | A0A3B3IRQ7 |
| ENSG00000163956 | ENST00000650182 | P30533 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36848531 | 2023 | Lrpap1 (RAP) Inhibits Proximal Tubule Clathrin Mediated and Clathrin Independent Endocytosis, Ameliorating Renal Aminoglycoside Nephrotoxicity. | 6 |
| 38035103 | 2023 | LRPAP1 is released from activated microglia and inhibits microglial phagocytosis and amyloid beta aggregation. | 0 |
| 36848531 | 2023 | Lrpap1 (RAP) Inhibits Proximal Tubule Clathrin Mediated and Clathrin Independent Endocytosis, Ameliorating Renal Aminoglycoside Nephrotoxicity. | 6 |
| 38035103 | 2023 | LRPAP1 is released from activated microglia and inhibits microglial phagocytosis and amyloid beta aggregation. | 0 |
| 34936547 | 2022 | The relationship of ADAMTSL2 and LRPAP1 gene methylation level with rheumatoid arthritis activity. | 1 |
| 34936547 | 2022 | The relationship of ADAMTSL2 and LRPAP1 gene methylation level with rheumatoid arthritis activity. | 1 |
| 34058195 | 2021 | Molecular chaperone RAP interacts with LRP1 in a dynamic bivalent mode and enhances folding of ligand-binding regions of other LDLR family receptors. | 3 |
| 34472763 | 2021 | Identification of intracellular glycosaminoglycan-interacting proteins by affinity purification mass spectrometry. | 4 |
| 34058195 | 2021 | Molecular chaperone RAP interacts with LRP1 in a dynamic bivalent mode and enhances folding of ligand-binding regions of other LDLR family receptors. | 3 |
| 34472763 | 2021 | Identification of intracellular glycosaminoglycan-interacting proteins by affinity purification mass spectrometry. | 4 |
| 31607522 | 2020 | Rhegmatogenous Retinal Detachment in Nonsyndromic High Myopia Associated with Recessive Mutations in LRPAP1. | 2 |
| 31607522 | 2020 | Rhegmatogenous Retinal Detachment in Nonsyndromic High Myopia Associated with Recessive Mutations in LRPAP1. | 2 |
| 29955130 | 2019 | LRPAP1 is a frequent proliferation-inducing antigen of BCRs of mantle cell lymphomas and can be used for specific therapeutic targeting. | 18 |
| 29955130 | 2019 | LRPAP1 is a frequent proliferation-inducing antigen of BCRs of mantle cell lymphomas and can be used for specific therapeutic targeting. | 18 |
| 26271838 | 2016 | Clinical Characterization of LRPAP1-Related Pediatric High Myopia. | 7 |
Citation
Dessen P
LRPAP1 (LDL receptor related protein associated protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2008-12-01
Online version: http://atlasgeneticsoncology.org/gene/50604/lrpap1
