LRRC25 (leucine rich repeat containing 25)

2014-11-01  

Identity

HGNC
LOCATION
19p13.11
LOCUSID
ALIAS
MAPA
FUSION GENES

Other Information

Locus ID:

NCBI: 126364
MIM: 607518
HGNC: 29806
Ensembl: ENSG00000175489

Variants:

dbSNP: 126364
ClinVar: 126364
TCGA: ENSG00000175489
COSMIC: LRRC25

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000175489ENST00000339007Q8N386
ENSG00000175489ENST00000595840Q8N386

Expression (GTEx)

0
50
100
150
200

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
292881642018LRRC25 inhibits type I IFN signaling by targeting ISG15-associated RIG-I for autophagic degradation.18
290441912017LRRC25 Functions as an Inhibitor of NF-κB Signaling Pathway by Promoting p65/RelA for Autophagic Degradation.9
285369422018LRRC25 plays a key role in all-trans retinoic acid-induced granulocytic differentiation as a novel potential leukocyte differentiation antigen.1
303408352018Loss of LRRC25 accelerates pathological cardiac hypertrophy through promoting fibrosis and inflammation regulated by TGF-β1.1

Citation

Dessen P

LRRC25 (leucine rich repeat containing 25)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/68603/lrrc25