LRRC3B (leucine rich repeat containing 3B)

2008-05-01  

Identity

HGNC
LOCATION
3p24.1
LOCUSID
ALIAS
LRP15

Other Information

Locus ID:

NCBI: 116135
HGNC: 28105
Ensembl: ENSG00000179796

Variants:

dbSNP: 116135
ClinVar: 116135
TCGA: ENSG00000179796
COSMIC: LRRC3B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000179796ENST00000396641Q96PB8
ENSG00000179796ENST00000396641A0A024R2R0
ENSG00000179796ENST00000414619C9JMC7
ENSG00000179796ENST00000417744Q96PB8
ENSG00000179796ENST00000417744A0A024R2R0
ENSG00000179796ENST00000432040C9J6A1
ENSG00000179796ENST00000456208Q96PB8
ENSG00000179796ENST00000456208A0A024R2R0
ENSG00000179796ENST00000648296Q96PB8
ENSG00000179796ENST00000648296A0A024R2R0

Expression (GTEx)

0
5
10
15
20
25

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
187574302008LRRC3B, encoding a leucine-rich repeat-containing protein, is a putative tumor suppressor gene in gastric cancer.17
223218172012LRRC3B gene is frequently epigenetically inactivated in several epithelial malignancies and inhibits cell growth and replication.12
221013832012Methylation pattern of the putative tumor-suppressor gene LRRC3B promoter in clear cell renal cell carcinomas.6
188159422009Epigenetic silencing of LRRC3B in colorectal cancer.4
183777272008The novel gene LRP15 is regulated by DNA methylation and confers increased efficiency of DNA repair of ultraviolet-induced DNA damage.1
248391122014The clinical value of LRRC3B gene expression and promoter hypermethylation in breast carcinomas.1
262763582016LRRC3B is downregulated in non-small-cell lung cancer and inhibits cancer cell proliferation and invasion.1
271186442016[LRRC3B is Downregulated in Non-small Cell Lung Cancer and Connected with Cell Proliferation and Invasion].0

Citation

Dessen P

LRRC3B (leucine rich repeat containing 3B)

Atlas Genet Cytogenet Oncol Haematol. 2008-05-01

Online version: http://atlasgeneticsoncology.org/gene/50140/lrrc3b