LRRTM1 (leucine rich repeat transmembrane neuronal 1)

2014-11-01  

Identity

HGNC
LOCATION
2p12
LOCUSID
ALIAS
-

Other Information

Locus ID:

NCBI: 347730
MIM: 610867
HGNC: 19408
Ensembl: ENSG00000162951

Variants:

dbSNP: 347730
ClinVar: 347730
TCGA: ENSG00000162951
COSMIC: LRRTM1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000162951ENST00000295057Q86UE6
ENSG00000162951ENST00000409148Q86UE6
ENSG00000162951ENST00000415098C9JF97
ENSG00000162951ENST00000416268C9JEE2
ENSG00000162951ENST00000417012Q86UE6
ENSG00000162951ENST00000433224Q86UE6
ENSG00000162951ENST00000452811C9JPM9

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Neuronal SystemREACTOMER-HSA-112316
Protein-protein interactions at synapsesREACTOMER-HSA-6794362
Interactions of neurexins and neuroligins at synapsesREACTOMER-HSA-6794361

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
210416082011Family-based analysis of genetic variation underlying psychosis-inducing effects of cannabis: sibling analysis and proband follow-up.48
210416082011Family-based analysis of genetic variation underlying psychosis-inducing effects of cannabis: sibling analysis and proband follow-up.48
206782492010Polymorphisms in leucine-rich repeat genes are associated with autism spectrum disorder susceptibility in populations of European ancestry.21
191253662009Where and what is the right shift factor or cerebral dominance gene? A critique of Francks et al. (2007).7
217081312011Bidirectional transcription from human LRRTM2/CTNNA1 and LRRTM1/CTNNA2 gene loci leads to expression of N-terminally truncated CTNNA1 and CTNNA2 isoforms.4
176679612007LRRTM1 on chromosome 2p12 is a maternally suppressed gene that is associated paternally with handedness and schizophrenia.0
191253652009Editorial commentary: is LRRTM1 the gene for handedness?0
191253672009Understanding the genetics of behavioural and psychiatric traits will only be achieved through a realistic assessment of their complexity.0
196260252009Supporting evidence for LRRTM1 imprinting effects in schizophrenia.0
247856882014The imprinted gene LRRTM1 mediates schizotypy and handedness in a nonclinical population.0

Citation

Dessen P

LRRTM1 (leucine rich repeat transmembrane neuronal 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/68671/lrrtm1