LSP1 (lymphocyte specific protein 1)

2004-05-01  

Identity

HGNC
LOCATION
11p15.5
LOCUSID
ALIAS
WP34,pp52
FUSION GENES

Other Information

Locus ID:

NCBI: 4046
MIM: 153432
HGNC: 6707
Ensembl: ENSG00000130592

Variants:

dbSNP: 4046
ClinVar: 4046
TCGA: ENSG00000130592
COSMIC: LSP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000130592ENST00000311604P33241
ENSG00000130592ENST00000381775P33241
ENSG00000130592ENST00000405957P33241
ENSG00000130592ENST00000406638P33241
ENSG00000130592ENST00000417766E9PBD8
ENSG00000130592ENST00000418975C9JDV1
ENSG00000130592ENST00000421485C9J9B9
ENSG00000130592ENST00000429923C9JU59
ENSG00000130592ENST00000432093E9PBD8
ENSG00000130592ENST00000446808C9JKF7
ENSG00000130592ENST00000451814C9JNQ1
ENSG00000130592ENST00000457279E7EMG9
ENSG00000130592ENST00000612798P33241

Expression (GTEx)

0
50
100
150
200
250
300
350

Pathways

PathwaySourceExternal ID
TuberculosisKEGGko05152
TuberculosisKEGGhsa05152

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
204538382010Genome-wide association study identifies five new breast cancer susceptibility loci.344
184372042008Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics.167
197180302009Carbohydrate-specific signaling through the DC-SIGN signalosome tailors immunity to Mycobacterium tuberculosis, HIV-1 and Helicobacter pylori.145
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
178273882007Genetic variation in 1253 immune and inflammation genes and risk of non-Hodgkin lymphoma.67
205547492010FGFR2 and other loci identified in genome-wide association studies are associated with breast cancer in African-American and younger women.59
206052012010Gene-environment interactions in 7610 women with breast cancer: prospective evidence from the Million Women Study.59
197893662009Evaluation of 11 breast cancer susceptibility loci in African-American women.56
224543792012Common breast cancer susceptibility variants in LSP1 and RAD51L1 are associated with mammographic density measures that predict breast cancer risk.50
196567742009Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers.49

Citation

Dessen P

LSP1 (lymphocyte specific protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2004-05-01

Online version: http://atlasgeneticsoncology.org/gene/289/lsp1