LTB4R2 (leukotriene B4 receptor 2)

2007-02-01  

Identity

HGNC
LOCATION
14q12
LOCUSID
ALIAS
BLT2,BLTR2,JULF2,KPG_004,LTB4-R

Other Information

Locus ID:

NCBI: 56413
MIM: 605773
HGNC: 19260
Ensembl: ENSG00000213906

Variants:

dbSNP: 56413
ClinVar: 56413
TCGA: ENSG00000213906
COSMIC: LTB4R2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000213906ENST00000527924E9PIC1
ENSG00000213906ENST00000528054A0A3Q5ACI7
ENSG00000213906ENST00000530080E9PNJ6
ENSG00000213906ENST00000533293Q9NPC1
ENSG00000213906ENST00000543919Q9NPC1

Expression (GTEx)

0
5
10
15
20
25
30

Pathways

PathwaySourceExternal ID
Calcium signaling pathwayKEGGko04020
Neuroactive ligand-receptor interactionKEGGko04080
Calcium signaling pathwayKEGGhsa04020
Neuroactive ligand-receptor interactionKEGGhsa04080
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class A/1 (Rhodopsin-like receptors)REACTOMER-HSA-373076
Eicosanoid ligand-binding receptorsREACTOMER-HSA-391903
Leukotriene receptorsREACTOMER-HSA-391906
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (q) signalling eventsREACTOMER-HSA-416476
Gastrin-CREB signalling pathway via PKC and MAPKREACTOMER-HSA-881907

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
346335772022Leukotriene B4 receptor 2 correlates with prognosis and immune infiltration in clear cell renal cell carcinoma.2
354267932022[Prognostic implications and functional enrichment analysis of LTB4R in patients with acute myeloid leukemia].1
364290342022LTB4R Promotes the Occurrence and Progression of Clear Cell Renal Cell Carcinoma (ccRCC) by Regulating the AKT/mTOR Signaling Pathway.3
346335772022Leukotriene B4 receptor 2 correlates with prognosis and immune infiltration in clear cell renal cell carcinoma.2
354267932022[Prognostic implications and functional enrichment analysis of LTB4R in patients with acute myeloid leukemia].1
364290342022LTB4R Promotes the Occurrence and Progression of Clear Cell Renal Cell Carcinoma (ccRCC) by Regulating the AKT/mTOR Signaling Pathway.3
346357802021Leukotriene B4 receptor-2 contributes to KRAS-driven lung tumor formation by promoting interleukin-6-mediated inflammation.3
348143482021Prognostic and immunological value of LTB4R in pan-cancer.2
346357802021Leukotriene B4 receptor-2 contributes to KRAS-driven lung tumor formation by promoting interleukin-6-mediated inflammation.3
348143482021Prognostic and immunological value of LTB4R in pan-cancer.2
305538122019Mediatory role of BLT2 in the proliferation of KRAS mutant colorectal cancer cells.3
305538122019Mediatory role of BLT2 in the proliferation of KRAS mutant colorectal cancer cells.3
293236992018Leukotriene B4 receptor 2 regulates the proliferation, migration, and barrier integrity of bronchial epithelial cells.6
297909962018DNA methylation and inflammation marker profiles associated with a history of depression.28
298988092018BLT2, a leukotriene B4 receptor 2, as a novel prognostic biomarker of triple-negative breast cancer.12

Citation

Dessen P

LTB4R2 (leukotriene B4 receptor 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43648/ltb4r2