LYNX1 (Ly6/neurotoxin 1)

2007-02-01  

Identity

HGNC
LOCATION
8q24.3
LOCUSID
ALIAS
-

Other Information

Locus ID:

NCBI: 66004
MIM: 606110
HGNC: 29604
Ensembl: ENSG00000180155

Variants:

dbSNP: 66004
ClinVar: 66004
TCGA: ENSG00000180155
COSMIC: LYNX1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000180155ENST00000613110A0A087WYG6
ENSG00000180155ENST00000614268A0A087WZS0
ENSG00000180155ENST00000614491P0DP58
ENSG00000180155ENST00000620006P0DP58
ENSG00000180155ENST00000621401P0DP58
ENSG00000180155ENST00000652477P0DP58

Expression (GTEx)

0
50
100
150
200

References

Pubmed IDYearTitleCitations
374376462023Lynx1 and the family of endogenous mammalian neurotoxin-like proteins and their roles in modulating nAChR function.2
374376462023Lynx1 and the family of endogenous mammalian neurotoxin-like proteins and their roles in modulating nAChR function.2
332998552020Increased Expression of LYNX1 in Ovarian Serous Cystadenocarcinoma Predicts Poor Prognosis.3
333749632020Spatial Structure and Activity of Synthetic Fragments of Lynx1 and of Nicotinic Receptor Loop C Models.4
332998552020Increased Expression of LYNX1 in Ovarian Serous Cystadenocarcinoma Predicts Poor Prognosis.3
333749632020Spatial Structure and Activity of Synthetic Fragments of Lynx1 and of Nicotinic Receptor Loop C Models.4
311504352019Water-soluble variant of human Lynx1 induces cell cycle arrest and apoptosis in lung cancer cells via modulation of α7 nicotinic acetylcholine receptors.16
311504352019Water-soluble variant of human Lynx1 induces cell cycle arrest and apoptosis in lung cancer cells via modulation of α7 nicotinic acetylcholine receptors.16
292068812017Deletion of lynx1 reduces the function of α6* nicotinic receptors.10
292068812017Deletion of lynx1 reduces the function of α6* nicotinic receptors.10
255718742015Aberrant NMDA receptor DNA methylation detected by epigenome-wide analysis of hippocampus and prefrontal cortex in major depression.25
260255032015Role of Lynx1 and related Ly6 proteins as modulators of cholinergic signaling in normal and neoplastic bronchial epithelium.19
260334902015Transcriptional regulation of SLURP2, a psoriasis-associated gene, is under control of IL-22 in the skin: A special reference to the nested gene LYNX1.10
255718742015Aberrant NMDA receptor DNA methylation detected by epigenome-wide analysis of hippocampus and prefrontal cortex in major depression.25
260255032015Role of Lynx1 and related Ly6 proteins as modulators of cholinergic signaling in normal and neoplastic bronchial epithelium.19

Citation

Dessen P

LYNX1 (Ly6/neurotoxin 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43968/lynx1