LYPD6 (LY6/PLAUR domain containing 6)

2014-11-01  

Identity

HGNC
LOCATION
2q23.2
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 130574
MIM: 613359
HGNC: 28751
Ensembl: ENSG00000187123

Variants:

dbSNP: 130574
ClinVar: 130574
TCGA: ENSG00000187123
COSMIC: LYPD6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000187123ENST00000334166Q86Y78
ENSG00000187123ENST00000392854Q86Y78
ENSG00000187123ENST00000409381Q86Y78
ENSG00000187123ENST00000414420C9IYE7
ENSG00000187123ENST00000418762Q86Y78
ENSG00000187123ENST00000651933Q86Y78

Expression (GTEx)

0
1
2
3
4
5
6
7

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
239875102013Lypd6 enhances Wnt/β-catenin signaling by promoting Lrp6 phosphorylation in raft plasma membrane domains.31
196531212010Identification and characterization of human LYPD6, a new member of the Ly-6 superfamily.10
273440192016Functional interaction between Lypd6 and nicotinic acetylcholine receptors.9
300698742018Structure of the Wnt signaling enhancer LYPD6 and its interactions with the Wnt coreceptor LRP6.2

Citation

Dessen P

LYPD6 (LY6/PLAUR domain containing 6)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/68720/lypd6