LYPLA2 (lysophospholipase 2)

2013-06-01  

Identity

HGNC
LOCATION
1p36.11
LOCUSID
ALIAS
APT-2,APT2,DJ886K2.4
FUSION GENES

Other Information

Locus ID:

NCBI: 11313
MIM: 616143
HGNC: 6738
Ensembl: ENSG00000011009

Variants:

dbSNP: 11313
ClinVar: 11313
TCGA: ENSG00000011009
COSMIC: LYPLA2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000011009ENST00000374501Q5QPQ0
ENSG00000011009ENST00000374502Q5QPQ3
ENSG00000011009ENST00000374503Q5QPQ2
ENSG00000011009ENST00000374505Q5QPN9
ENSG00000011009ENST00000374514O95372
ENSG00000011009ENST00000374514A0A140VJC9
ENSG00000011009ENST00000420982Q5QPQ1
ENSG00000011009ENST00000421070Q5QPN5

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
Glycerophospholipid metabolismKEGGko00564
Glycerophospholipid metabolismKEGGhsa00564
Developmental BiologyREACTOMER-HSA-1266738
Axon guidanceREACTOMER-HSA-422475
L1CAM interactionsREACTOMER-HSA-373760

References

Pubmed IDYearTitleCitations
211520832010Acyl-protein thioesterase 2 catalyzes the deacylation of peripheral membrane-associated GAP-43.41
233969702013Dynamic palmitoylation links cytosol-membrane shuttling of acyl-protein thioesterase-1 and acyl-protein thioesterase-2 with that of proto-oncogene H-ras product and growth-associated protein-43.33
258499162015Enzymatic protein depalmitoylation by acyl protein thioesterases.18
253019512014Identification of the major prostaglandin glycerol ester hydrolase in human cancer cells.5
304828052019Lysophospholipases cooperate to mediate lipid homeostasis and lysophospholipid signaling.0

Citation

Dessen P

LYPLA2 (lysophospholipase 2)

Atlas Genet Cytogenet Oncol Haematol. 2013-06-01

Online version: http://atlasgeneticsoncology.org/gene/53384/lypla2