MAGEA6 (MAGE family member A6)

2003-10-01 Affiliation

Identity

HGNC

MAGEA6

LOCATION

Xq28

LOCUSID

4105

ALIAS

CT1.6,MAGE-3b,MAGE3B,MAGE6

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 4105
MIM: 300176
HGNC: 6804
Ensembl: ENSG00000197172

Variants:

dbSNP: 4105
ClinVar: 4105
TCGA: ENSG00000197172
COSMIC: MAGEA6

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000197172	ENST00000329342	P43360
ENSG00000197172	ENST00000412733	E7EUF2
ENSG00000197172	ENST00000457643	E7ETG4
ENSG00000197172	ENST00000616035	P43360

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
25679763	2015	Degradation of AMPK by a cancer-specific ubiquitin ligase.	99
12208877	2002	Disease-associated bias in T helper type 1 (Th1)/Th2 CD4(+) T cell responses against MAGE-6 in HLA-DRB10401(+) patients with renal cell carcinoma or melanoma.	74
12631591	2003	MAGE-6 encodes HLA-DRbeta1*0401-presented epitopes recognized by CD4+ T cells from patients with melanoma or renal cell carcinoma.	16
25564441	2015	A Comprehensive Expression Analysis of Cancer Testis Antigens in Head and Neck Squamous Cell Carcinoma Revels MAGEA3/6 as a Marker for Recurrence.	13
30056111	2018	miR-1273g silences MAGEA3/6 to inhibit human colorectal cancer cell growth via activation of AMPK signaling.	10
29024810	2018	MAGEA6 promotes human glioma cell survival via targeting AMPKα1.	8
18197853	2008	Expression of melanoma-associated antigens in oral squamous cell carcinoma.	7
22134685	2012	MAGE A1-A6 RT-PCR and MAGE A3 and p16 methylation analysis in induced sputum from patients with lung cancer and non-malignant lung diseases.	7
29448247	2018	Knockdown of MAGEA6 Activates AMP-Activated Protein Kinase (AMPK) Signaling to Inhibit Human Renal Cell Carcinoma Cells.	4
22707303	2012	Identification of novel MAGE-A6- and MAGE-A12-derived HLA-A24-restricted cytotoxic T lymphocyte epitopes using an in silico peptide-docking assay.	2

Citation

Dessen P

MAGEA6 (MAGE family member A6)

Atlas Genet Cytogenet Oncol Haematol. 2003-10-01

Online version: http://atlasgeneticsoncology.org/gene/41249/magea6