MAGEC2 (MAGE family member C2)

2003-06-01  

Identity

HGNC
MAGEC2
LOCATION
Xq27.2
LOCUSID
51438
ALIAS
CT10,HCA587,MAGEE1

Other Information

Locus ID:

NCBI: 51438
MIM: 300468
HGNC: 13574
Ensembl: ENSG00000046774

Variants:

dbSNP: 51438
ClinVar: 51438
TCGA: ENSG00000046774
COSMIC: MAGEC2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000046774ENST00000247452Q9UBF1

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
189427082009Frequent expression of the novel cancer testis antigen MAGE-C2/CT-10 in hepatocellular carcinoma.24
229259302012Analysis of the processing of seven human tumor antigens by intermediate proteasomes.24
217549862011MAGE-C2/CT10 protein expression is an independent predictor of recurrence in prostate cancer.21
149997772004Two new tumor-specific antigenic peptides encoded by gene MAGE-C2 and presented to cytolytic T lymphocytes by HLA-A2.18
217386562011Expression of MAGE-C1/CT7 and MAGE-C2/CT10 predicts lymph node metastasis in melanoma patients.17
218767672011MAGE I transcription factors regulate KAP1 and KRAB domain zinc finger transcription factor mediated gene repression.17
230967062013MAGE-C2 promotes growth and tumorigenicity of melanoma cells, phosphorylation of KAP1, and DNA damage repair.17
246873772014MAGEC2, an epithelial-mesenchymal transition inducer, is associated with breast cancer metastasis.15
174959642007Epigenetic control of MAGE gene expression by the KIT tyrosine kinase.12
206210942010Expression and prognostic relevance of MAGE-C1/CT7 and MAGE-C2/CT10 in osteolytic lesions of patients with multiple myeloma.12

Citation

Dessen P

MAGEC2 (MAGE family member C2)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/41264/magec2