Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9794
MIM: 605424
HGNC: 13632
Ensembl: ENSG00000161021
Variants:
dbSNP: 9794
ClinVar: 9794
TCGA: ENSG00000161021
COSMIC: MAML1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000161021 | ENST00000292599 | Q92585 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34818576 | 2022 | Elucidated tumorigenic role of MAML1 and TWIST1 in gastric cancer is associated with Helicobacter pylori infection. | 4 |
| 36155393 | 2022 | Cottontail rabbit papillomavirus E6 proteins: Interaction with MAML1 and modulation of the Notch signaling pathway. | 1 |
| 34818576 | 2022 | Elucidated tumorigenic role of MAML1 and TWIST1 in gastric cancer is associated with Helicobacter pylori infection. | 4 |
| 36155393 | 2022 | Cottontail rabbit papillomavirus E6 proteins: Interaction with MAML1 and modulation of the Notch signaling pathway. | 1 |
| 31874246 | 2020 | ZBP-89 negatively regulates self-renewal of liver cancer stem cells via suppression of Notch1 signaling pathway. | 13 |
| 32179552 | 2020 | MAML1-Dependent Notch-Responsive Genes Exhibit Differing Cofactor Requirements for Transcriptional Activation. | 6 |
| 32180088 | 2020 | MAML1 promotes ESCC aggressiveness through upregulation of EMT marker TWIST1. | 10 |
| 32482852 | 2020 | MAML1/2 promote YAP/TAZ nuclear localization and tumorigenesis. | 27 |
| 31874246 | 2020 | ZBP-89 negatively regulates self-renewal of liver cancer stem cells via suppression of Notch1 signaling pathway. | 13 |
| 32179552 | 2020 | MAML1-Dependent Notch-Responsive Genes Exhibit Differing Cofactor Requirements for Transcriptional Activation. | 6 |
| 32180088 | 2020 | MAML1 promotes ESCC aggressiveness through upregulation of EMT marker TWIST1. | 10 |
| 32482852 | 2020 | MAML1/2 promote YAP/TAZ nuclear localization and tumorigenesis. | 27 |
| 30370525 | 2019 | Knockdown of MAML1 inhibits proliferation and induces apoptosis of T-cell acute lymphoblastic leukemia cells through SP1-dependent inactivation of TRIM59. | 6 |
| 30732857 | 2019 | MAML1 regulates EMT markers expression through NOTCH-independent pathway in breast cancer cell line MCF7. | 6 |
| 30992079 | 2019 | Role of MAML1 in targeted therapy against the esophageal cancer stem cells. | 23 |
Citation
Dessen P
MAML1 (mastermind like transcriptional coactivator 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47260/maml1
